Alzheimer's Disease – Pathology, Tangles, Beta Amyloids

48 comments

  1. Sir asalamualaikum myself dr tahir ansari from gsvm medical college kanpur up india & my view for your lecture that your lecture erase my false concept about plage nad tau protein jajakkallah sir ji

  2. The BEST VIDEO AVAILABLE!!! This gentlemen Covers everything related to Alzheimer s from genes to pathology. Awesome presentation!

  3. Sir, then how to prevent this abnormal process of Aβ.., is there any relevant solution present.., ?? or after the detection of AD what are those processes to follow for the cure…, I am a research scholar and I'm working on the biosensor part to detect AD. I'm a physics student and I don't know much of the biological activities of AD. but then this lecture helps me a lot..,
    so thank you so much for the valuable lecture. It is surely a beneficent one for me!!

    Thank You so much, Sir!!!

  4. This is amazing! You definitely have a talent for teaching, thank you for making this available!!

  5. Ur explanation helped made me understand a lot of holes in other lecturers explanations on the whole progression of alzheimers onset in an individual. Thank you so much!! Info will now be in my head for my final exam 🙂

  6. Veryy goooood sir it really helps in my todays presentation…..very simple understanding..
    .i wish that u were in our college…

  7. Hi, thanks for the video. I was wondering when the cell gets destroyed through the combined work of amyloid plaque and tau tangles, what remains. Does the neuron itself disappear leaving the tau tangles and amyloid plaque behind? Or does the neuron body remain, like dead debris in the brain?

  8. Very reliable explanation; easy to understand ;best alzeimer lecture ever on youtube…you make every point clear sir;thanks for helping us sir….☺

  9. I am not a student ,but my mother's sadly has Alzheimers ,I feel I have learnt something from this lecture, I now have a better understanding of what's actually happening. I thank you for sharing your knowledge.

  10. 1) physiologically the fragments are degraded in the proteassome
    2) with the existence of b secretase instead, we have an accumulation of fragments that can't be degraded by the proteassome, so they accumlate
    3) since they're lipoproteins, they accumulate in the extracellular fuid

    something doesn't make sense to me: there are only proteasomes intracellularly (right?), so how come the senile plaque forms outward? should the physiological fragments not also accumulate outside bc there is no extracellular proteasome?
    thanks for the lecture !

  11. Is it hyper polarization or hyper phosphorylation and does Tau is the integral part of micro-tubules.

  12. Does Beta amyloid Protein is lipo-protein, if yes what is the lipid part in this. Secondly, how the amyloid proteins are pulled out and deposited as senile plaques means what would be the mechanism for coming out and deposited externally as senile (amyloid) plaques.

  13. Sir I follow ur immunology lectures ur anatomy and physiology lectures as well
    Am in mbbs first year
    Ur explanations helped me lot ND u know wt the cut copy paste of ur presentations in mine brought me many applause from my Dean as well.. Everyone in my college treat me as one of the most intelligent doctors but only I know it's only bcoz of u
    Thanq so much sir
    Thanq is a word which is not really enough to describe ur help but I can promise you that someday I will be a good doctor
    But still it's bcoz of u

  14. Sir upto yet lecture is not uploaded of diabetes management …and sir u promise to me that I will upload it soon….plz upload sir.

  15. Another point….the focus of the camera should be right on the board so that students can have a closer look at what is being written/drawn….sorry…I'm going to lecture on neurodegenerative diseases and am watching these videos for tips…:…

  16. Sorry…good lecture….but it seems the lecturer has mistakenly written recurrent functions instead of recurrent infections…..

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