Intermittent Fasting is MEDICINE: Reversing Diabetes & Obesity ft. Dr. Jason Fung || #61



as a doctor you can't face that you can't face that you have no idea what the hell you're doing right so then therefore you have to change the fact that it's not reversible its chronic and progressive and I'm doing the best that I can it's like aging you might want to get young but there's no way you always get older 90 diabetes you say it's the same thing but it's not true and that's the problem is it's not true and it's a reversible disease and it comes down to this what we did was we took a disease that's essentially a dietary disease and we gave a lot of drugs and then we wonder why isn't your diabetes getting better because we're giving you drugs to treat the blood glucose but here's the thing we're giving all these were so focused on treating the blood glucose that we forgot to treat the diabetes hey listeners welcome to this week's episode of the human enhancement podcast and I'm really excited to bring back one of our most popular guests ever on this program dr. Jason Fung it's been about almost two years now and for those that are new listeners or one a reminder dr. Jason Fung is a doctor obviously but specializing in nephrology a section of internal medicine but I think what he's really become a world leading expert on is intermittent fasting low carb high fat diets especially in a clinical use case he's a founder of intensive dietary management which has treated thousands of patients and managing their metabolic syndromes through fasting in lockup high fat diets and also co-author of two best-selling books obesity code and the complete guide to fasting welcome back to the program oh thanks for having me the yeah it's been great is just saying it hasn't seemed like two years flown right by great to be here yeah and I think that just thinking about the momentum I think two years ago we were just starting to get into fasting as a community with we fast I think we had maybe a couple thousand people I most know were you know over 20,000 people plus and group now and I think you know that was around the time you know the complete guide of fasting you know BC code I think we're published around 2016 I think we chat in 2016 so just when your books just started coming out and but even at that time you had huge following as these books are being released so you know what is it like from your experience I mean we can I can share a little bit of what it's like over the last two years from my experience and what we've seen the community grow but I'm sure sort of in the center as one of the I would say the key thought leader in around a lot of these topics what it's what has it been like for you yeah it's been very interesting because we're seeing it sort of move into sort of areas that you would never have thought so for example I come at it from a very medical sort of standpoint so I do kidney disease I deal with a lot of type 2 diabetes so that's been my focus I treat a lot of type 2 diabetics and I'm all about weight loss getting people off their medications reversing their type 2 diabetes and that was my sort of initial interest in it but there's so many different reasons that fasting can be beneficial for somebody that we're seeing it in elite athletes for example we're seeing it in people doing martial arts and Ultimate Fighting sort of thing we see all these people are doing talking about training in the fast state so it's really a Natasia about cancer we see about Alzheimer's disease so all these different areas that can benefit but are really people starting to really think about why they're so beneficial from a medical standpoint so when I started doing this about five years ago boy everybody thought I was crazy understand a few people thought I was crazy except for you maybe that was about it but from a medical standpoint it's changed because now you're seeing it discuss you know on the Today show it's been discussed on the doctors you discussed on different show so it's actually getting out there now there's just a lot of skepticism no but all these people are talking about it and for example I'm coming down to San Diego for the conference the spring conference which is the obesity medicine Association which is the largest association of obesity specialist and I'm doing the keynote so it's like okay well we went from boy this guy's a real quack – hey what can we actually learn about fasting that may give us an option and that's sort of the way I had always positioned it is like nobody has to do it but it's an option for you don't don't eliminate your options because it may work very well for people and some people is a great option some people it's not a very good option but the bottom line is that you need to keep your options open yeah so why not do it and and that's it there's been a very large change so even amongst the medical community which is one that I obviously spend a lot of time in I speak at medical conferences and I speak at sort of local talks to doctors and you see that there's this real growing acceptance that hey we should really think about this because it makes a lot of sense and then from from your standpoint you see this sort of huge interest like the this huge wave of interest you see intermittent fasting on all kinds of sort of mass media social media the the interest is really getting to sort of you know it's a fever pitch it's it's it's great yeah I mean I think part of it is one people are trying and seeing good results but – I think that published it it's becoming more and more compelling I mean like Marc Madsen at the NIH as publishing could work there's a bunch of researchers in the broad fasting ketogenic diet ketosis space that are I think doing good work on the RCT side just publishing good good work and I think you know it is it seems interesting I think there's a other you know I would say you know companies or groups around killing diets like Verta health publishing interesting results by the qjt diet reversing a lot of endpoints of type 2 diabetes I think it's one a perfect storm of data out of peer-reviewed journals – clinicians like yourself seeing good results with patients and then I think the end persons themselves are like saying hey like I unlike off my insulin meds I'm off my diabetes meds I feel way better I've never like been this healthy I something is working right I mean I think yeah absolutely yeah I think that the the thing is that ketogenic diets and intermittent fasting are sort of related approaches because in the end what they're trying to do is really lower insulin sort of the acknowledgment that too much insulin is really the underlying cause of obesity and type 2 diabetes they're both sort of diseases of hyperinsulinemia which is a word that means too much insulin in the blood so if hyperinsulinemia is the cause of all this we used to say that oh these are diseases of insulin resistance but that doesn't help you because then it's like okay then what causes insulin resistance you could say meat causes it then you should eat less meat that didn't really work but if you understand that the cause of these diseases is hyperinsulinemia then it leads you to say okay well if you have too much insulin how are you gonna lower insulin because a lot of drugs are not gonna do that for you right one way to do it is cut the carbs to sort of a very low level which is a ketogenic diet another way to do it is intermittent fasting because again if you don't eat anything your insulin levels are going to drop and that's sort of what I talked about I have a book coming out in another booklet called the diabetes code which is sort of the follow-on to the obesity code which explains sort of what type-2 diabetes is and how that lowering insulin is really the key to treating the diabetes rather than taking a bunch of medications that are just gonna make things worse right so the ketogenic diet and fasting they're sort of sort of related in that way and you see that where one does well the other also does well further house is very interesting because they came out with that data in type 2 diabetes showing that a ketogenic diet could do very well for type 2 diabetes but interestingly they don't endorse fasting at all they actually hate the stuff yeah I'm not to cure so yeah I yeah let's tease into that I mean I think I think you that is the you know I think what you said you know aligns with my understanding of the space and research in the space that there are different forms of lowering or approaching the hyperinsulinemia problem can you talk about the pros and cons and also your clinical experience with AF and you know a low-carb or a ketogenic diet you know how do you actually see this in practice versus being more on the dogmatic side of like one versus the other do you see I mean I think what you just said it sounds like they're more hand-in-hand to both tools to be utilized do you think there's a conflict there do you use them together what have you seen in your crack I use them I use them together and that this is the way we approach it is that it's a it's a toolbox so that if one person really hates fasting okay well then don't do it because you hate it and you're never gonna do it so therefore use more on the diets I think you got to be a little bit stricter on the diet maybe more sort of ketogenic which is sort of less than 20 grams of carbs as opposed to say just low-carb which is maybe 50 even a hundred grams of carbohydrates because if you combine a low-carb approach with fasting then you sort of get the same idea if you don't like the fasting that you go to ketogenic diets and that's sort of the clinical approach because everybody's different so we work with people individually we have a program called the intensive dietary management program so that you can get counseling you can get or you can just join the membership and of get sort of updates regularly and the point is that there isn't the one-size-fits-all it's not like everybody should be doing the same thing because we're all individuals so maybe you need this and maybe you need that but there's always gonna be workarounds that we can get you to the place that you want to go and if if you can't do the fasting maybe it's because you don't have the proper support maybe you don't have something that helps you screw with the hunger and all that sort of stuff and that's what we're working on developing as well you know getting some things to help people with it because what in medicine the thing is that it's strange because we know that weight loss is difficult and if you don't eat you're gonna lose weight well there's not much brain power involved in understanding that so if you don't eat you lose weight then well that's great that's one way of losing weight that's not particularly unhealthy for you the K that the pushback that we always get is that oh nobody's ever gonna be able to do it it's like one that's not true because we've done one with thousands of people right and you have in your group you said 20,000 people so there you go 20,000 people we also know that billions and billions of people around the world do it as part of their religion so if you do Ramadan if you do fasting during Lent if you do Yom Kippur you know yeah exactly there's so many different fasting regimens Judaism Hinduism all this stuff so literally billions of people around the world to it but yet the push back is always well you'll never do it but in medicine if we say something's really hard but you need to do it you don't say oh well forget about it like you know for chemotherapy sucks right so you're just gonna die okay there's no way to be a doctor right it's like okay here's something hard but you need to do it so we're gonna help you we're gonna create these medicines that are gonna help with the pain we're gonna create these nausea medications we're gonna put you in a hospital if you need to to get through the chemotherapy that's what we do we say how can we help it with fasting we say well you know yeah fasting you'll take away your type-2 diabetes but you'll never do it so forget it just take your insulin shot like what are you talking about that's the way to be a doctor yeah it's hard so let me help you how can we help you can we create support groups like what you've done with your we fast groups can we create you know tea and stuff that may help with with the fasting then we do other things like give people information give them books so that they understand sort of what they're getting into sort of what to expect when fasting sort of thing I mean we have this book that's been on the bestseller this for like 50 years what to expect when expecting because again we know pregnancy is hard so let's tell you what's coming up so that you can prepare for it we don't have a what to expect when fasting which is what you know the reason I had to write that book the complete guide yeah no let's talk about like those three aspects I mean let's talk about the complete guide to fasting and then the new book I'm actually curious to hear you know I think to me the obesity code one of the core arguments was that sort of the calories and calories are out argument in terms of weight management was sort of outdated and you know we should think about you know it obesity as a hormone or insulin a problem so curious to see how diabetes code expands upon that – you mentioned teas or other interventions assist with fasting I know the either recently announced a partnership with peak tea so let's talk about that a second and then third I'm actually curious to just zoom out and just you know for folks that just getting into fasting or just learning about it we talked about you know individual personalized programs but if you could just sort of summarize you know again this is a say that you know basically you said if everyone's individualized but I'm going to just say if you were to say hey what is like a protocol could typically look like could we first talk start with a typical protocol and then go into the book and and other topics yeah so the protocols we use a couple of different sort of core protocols so for older people obviously we're gonna go more towards a shorter fast so you might do something like time restricted eating so sixteen eight sort of a protocol so the last sixteen eight yeah yeah I mean this is for like we're talking like 75 80 year olds right we're not talking like a little older like 45 like me okay you just got to be a bit more careful these these people a bit more frail I mean we treat very serious disease and we treat a lot of older people because that's my core sort of population group that I see so for older people yes seventy years old above we're gonna be a lot more cautious for you if you're on a lot of medications again we're gonna be a lot more cautious for you and then we're gonna make sure that you have the physician that is going to adjust your medications ahead of time so that you're not getting into problems if you're not on medications and you don't have to be quite as careful about that the as you get sort of opt the next step would be sort of like a 24-hour our protocol which is also sometimes called one meal a day so if you go from say breakfast breakfast or lunch to lunch or dinner that's about 24 where you're not eating yeah and that's for a pretty good regimen again not particularly severe but enough to kind of get people into it and also create some good weight loss which can be sustained fairly easily so it's especially good and this is what I do a lot of myself as the 24-hour fast because honestly it it slides right into your working day so I'm I'm 44 for turning 45 I have kids so it's really easy for me to skip breakfast and lunch because nobody knows if you miss breakfast a lot of people just drink coffee anyway right and half the time nobody knows if it's lunch either and I work right through so that gives me a lot of extra time and I'll say that I typically do more fasting when I'm really busy because then I gain time so today I'm fasting that's great because it's like yeah now I can fit it in it's no big deal for me it doesn't really matter to me because I know that my body will provide the energy that it needs but then I get an extra hour and I can I can fit in all this extra stuff you multiply that by weeks and years and it's like oh you get all this extra stuff done it's like yeah because spending all day figuring out where to eat yeah so the 24-hour schedule fits in very nicely into the working day and then that leaves you your evening to have dinner with your family and to go out to dinner with your friends and it doesn't disrupt you in any big way and you're not doing it every single day I'm not doing it every single day but three times a week maybe twice a week depending on what your goals are and that's one of them poor sort of messages in the IDM program is that you gotta realize that the fast thing is not particularly fun some people like it but if your goal is to lose weight then then then you know change your regimen so you do that if it's type-2 diabetes which is a more severe condition that can have health consequences then you gotta you got to be a bit more severe I mean I remember I was doing it fairly religiously for a little while and then I realized you know I'm doing it not for any particularly good reason as in my weight was around where I've always been my ways sighs was fairly ideal I don't have type 2 diabetes and stuff so I was doing it just for the heck of doing it because I was talking about it so then I was like I don't really need to do it that often and now it's more of a time management well me than anything else but that's my goal now so if my goal is to be able to write my box and to do those podcasts and do the blogs and stuff that's as good a reason as any yeah then I'm gonna do more not but I I know where my goal is it's not simply just a matter of this and some people have these different goals so it's hoffa G which we sometimes I don't know we talked about before but their goal is etapa G so yeah you're not gonna you're gonna do it different you're gonna get more into the law slightly law class and you're gonna do a water only fast that bone broth is you're not gonna do it like you gotta stick to the water only so if your goal is to etaf again the benefits could be huge but they're mostly theoretical right now then keep that in mind when you're choosing your regimen and then as we go into type 2 diabetes we typically go into the longer ones and the more medically supervised one so 36 hours is sort of a standard regimen three times a week if they're on medications particularly the insulin we have to adjust that before they go on and then for severe diabetes and this is where this is you have to be very careful as we start going into sort of extended fast where and the reason we do this is that we see a lot of people with severe diabetes and are on the verge of developing and organ damage that is eye damage kidney damage nerve damage and so on if you don't get that controlled right away once they develop it you can't reverse it it's like the oil in your car if you never change the oil in your car and then it breaks down then you say okay now gonna change the oil in my car – it doesn't work yeah same thing if you've shot your kidneys out it's too late I can get your kidney I can't can't your diabetes reversed but I can ask on your like your arm is third leg is chopped off right exactly yeah but those people will go into longer fast but again we know why we're doing and we've got it a goal in mind to reverse their diabetes very quickly so that they will have the best as possible of reversing their disease and type 2 diabetes is really the sort of one of the areas that I'm really focused on because it causes so much disease that is it's not simply a weight thing it's it's dialysis its blindness its amputations it's heart attacks its strokes it's cancer it's a lot of human suffering all related to diabetes and as a physician that's sort of my goal area but I acknowledge that there's tons of other areas so people come to me for cancer for example I'll switch the regimen there are there people who want to do training like sort of a lead athletes and I'll adjust the regimen based on that yeah and the other end points beyond just the time are you measuring glucose ketones are you doing blood panels for lipids inflammation markers or often checked a baseline blood test for everybody and that's more of a sort of cover-your-ass sort of move because you don't want to get blamed afterwards right so I will check a fairly detailed panel and everybody although I rarely find any problems the one problem I do find sometimes and type 2 diabetes is a low vitamin b12 level because metformin which is a very common medication can actually cause b12 deficiency so the last thing I want to do is find out after they've been fasting that their b12 is low and somebody says hey that's because they're not eating I'm like no I pick them up like all the time so I picked them up way before and I was checked the iron for example because I don't want somebody to come back to me and say oh they've been fasting and now their iron deficient because I picked it way up I've picked that iron deficiency up at the beginning and and then everything how often are you in these checkpoints sort of before and after a program are you doing like you know weekly or daily check yeah again it depends on the situation if you're more if it more serious and more yeah exactly so for like two diabetes for example there's a fairly standard marker called the a1c which is a three-month average so I'll often do bloodwork every three months so to check up on that if it's just weight loss and not diabetes there's no reason to do it more than once or twice a year sort of assuming that everything is going well not going well of course adjust and kind of go from there yeah and I think it's an interesting segue into just adjustments right so I think a lot of people in our groups always ask oh should I drink you know one of the recommends Bruin bone broth MCT oils coconut oils green tea coffee what are your thoughts I mean I think you know I think your point around bone broth perhaps not being ideal for tricking our tofu cheese because as you know there's amino acids and amino acid triggers mTOR which is what is i pathi sized to control or mediate sitaji you probably don't want bone broth for an tava tree crutch exactly but for like diabetes it'd be perfectly acceptable bit of amino acid it's not gonna do anything to you it's not gonna it's gonna have so little effect and same for a lot of people ask about bulletproof coffee and MCT oils again so you've got calories but you've got very little insulin effect so again if your if your point is to try and lower insulin effect for weight loss for diabetes hey that's great then you are going to be able to take the bulletproof coffee or MCT oil and still get like the lowering of insulin that you want so in keeping your goals in mind you'd say okay well that'd be perfectly fine for type 2 diabetes bone broth and typically we'll use bone broth for a more longer fast thirty six hours plus something like something like the bulletproof coffee is sort of acceptable from from an insulin standpoint but again it's it's it's sort of understanding what your goal is green tea is a very interesting substance and I've been talking a bit more about that lately and so it's just to get into that topic it's it's one of the things that has traditionally if you look at traditional Chinese medicine is actually one of the substances that has been always purportedly helpful for weight loss and if you look at the studies what's interesting is a couple of things one is that green tea when you give it as in a study typically has much higher levels of the catagen so the catechins are the antioxidants and the flavanols the compound that's thought to be responsible and it's but they're much higher doses there are like 10 cups a day sort of level which most people don't get to but that's what the studies are at and it shows that you can lose about an extra kilogram of weight with that what the catechins do is they block an enzyme called comt and comt is responsible for breaking down noradrenaline so if you block the comt noradrenaline goes up so what happens is that you get this activation of the sympathetic nervous system and your energy expenditure can go up by about 4 percent so not a huge increase but significant so essentially when you're losing weight a lot of the problems come when your your metabolic rate is going down so if you can take the green tea catechins and increase your metabolic rate that's huge the other thing that they showed in this study from just like 2016 is a randomized control trial is that you can when you compare it to placebo you get a reduction in ghrelin so ghrelin is a hunger hormone and if you lower ghrelin you have less hunger which is exactly what you detentions interesting green tea catechins absolutely and it's very interesting so it's like that's great because that's the main problem with weight loss is that you have too much hunger and your metabolic rate is slowing that's why people fail with weight loss now you have an all natural substance that people have been using for thousands of years that increases your metabolic rate and lowers your hunger and that's what people tell us all the time they drink green tea and then their hunger sort of goes away and it's like that's fantastic but you have to get to be up on the studies oh the other interesting thing is that age looks at different awesome tasks caffeine's also known via appetite suppressants or they can what were they controlling for that or is it uh or was an additive effect okay yeah it's an additive effect in fact when you compare catechins and caffeine or caffeine alone you get better effect with the cabouchins plus caffeine so it's you go like that they actually have a batter of fact so what caffeine does it Laxus other enzyme called phosphodiesterase which also raises the noradrenaline so they actually work through different pathways and of course normal green tea has both catechins and caffeine you can decaffeinate it but I don't recommend it because if you're want the benefit you got to have both of them to get you know twice the benefit so it's just saying it's interesting because in some of the studies they show that Asians actually get a better weight loss effect and vacations cause so you get an average weight loss of 1.5 kilos for Asians versus point 8 kilos for occasions and the reason is that Asians have a higher incidence of this high activity Co comt so that's the enzyme that's being blocked by green tea so if you're Asian and you have a lot of activity of the comt blocking it is gonna give you a better effect so it's like okay that's really fascinating but nevertheless point eight kilos is still a pretty good effect even for vacations but it may even be better for Asians which is huge because you look at the obesity epidemic and like China and stuff it's like massive like that because the numbers are huge over there but in any case it's it's just like wow that's fascinating so but the problem was so I recommend this in for people but then the problem is that the dose of catechins have to have is very high you have to have like 10 cups a day which isn't feasible for most people and that's where we worked with peak tea so what's interesting about peak tea first their tea is really great I love this stuff what they do is different it's an organic green tea and they get it from a single plantation but they do this cold brew crystallization where they actually steep it so you could probably do it yourself you take green tea and you put water so like cold coffee you can make yourself you put it overnight in the fridge and you let it sit for like eight hours and then because you're extracting the catechins at low temperature you get more of it out so you get like 2/3 the times the amounts of these like that a steeping process doesn't break the breaks down some of these complex molecules if you're cold doing it exactly the hot brew well will will not get as much because you don't have the time in contact with it so just like cold brew coffee you go to Starbucks you pay like twice the price for this cold brew because it's actually hard to make this is the same thing but what they've done is they cold brew it and then they sort of dehydrated so it's basically crystals of concentrated tea that's all it is it's a whole food it's not like what they do in the studies which is kind of industrially extract the catechins and then add it to the tea this is sort of a just concentrated cold brew tea that's all it is but it's in a single serve packet and then you mix it up and you drink it it's terrific and it's a little bit more obviously than just like coffee it's a little bit more but if you want to get that benefit so that then what we did with is we've created sort of blend for fasting specifically so we've made two sort of flavors one is with matcha which gives it a bit more body and helps with the sort of appetite suppressing the hunger and then we did this ginger citrus because some people have this kind of gurgling stomach and some issues with that and we found that ginger and also citrus is is helpful for that and you know personally I drink green tea plain so I don't like the flavors myself but those those are supposed to help like that's what a lot of our patients sort of tell us so that's why we've done and created a line sort of specifically for tea which is not something that's really been readily available because you know we have we have people to help with all kinds of stuff but then when you're fasting it's like oh yeah you're like out of luck like just do it man just man up and it's like okay well you don't do that for anybody else we create stuff to help them so because nothing was available we created this I mean bulletproof coffee is sort of this a similar idea but it's it's it's different I mean that's people use as a sort of fasting aid as well they don't always say that but that's essentially what they do it's basic what they're doing but I think the thing I think kind of funny with bulletproof coffee is that you're eating like 500 calories of fat so just like you're getting a lot of calories I think though the thing is like you see some people on a kid drink diet just like at a certain point it's still like you're eating a lot of calories and you just hardly wait if we're just eating like 3,000 calories with butter so I like I like the I like the tea cuz again it's like very a caloric if there's no any calories probably close to close enough and it sounds like there's like what a 3 for X amount of Katich instead of having to drink 10 cups you can drink 2 cups yeah 2/3 tops and you're good and and it's still a it's still a whole food it's really just cold brew tea it may help you the fasting then you get all the benefits and it makes it a little bit easier for you and that's the whole point is to really try to make something that well how people like obviously if it doesn't help you then don't take it right that there's no point but if it helps you then hey you're gonna get a lot of benefit from the fasting and if that's helps you fasting hey Greek that's that's terrific so piq e PP i– q ue t so folks are interested I've had it before I remember seeing some of their product I think out in San Francisco so yeah it's good T give it a spin for our listeners out there I mean I think with the interest of like adjuncts the fasting I mean I think one thing that we saw that's interesting from a keto nester perspective one of our products was a paper published kind of actually near your backyard you BC you managed to British Columbia showing that acute use of Quito Nestor actually reduces glycemic response so what that means is that a kiddo Nestor versus placebo for a sugar test so oral glucose tolerance test which is kind of a standard test a test for insulin resistance or sensitivity reduce the glycemic response I'm curious to get your thoughts on that if you've had a chance to review a paper yeah yeah and there's awesome exogenous ketones broadly I think exogenous ketones have a role to play and this is this kind of goes along with the sort of fasting aids and sort of thing because it's not quite a whole food obviously but again it's something that may help along the way so there's a couple of things one is that the sort of properties of ketones have not been well appreciated for a long time I don't think anybody really looks at it ever so but lately with sort of this interest in the ketogenic diet you're getting these really really interesting things popping up like oh hey you can treat seizures with it oh hey you can enhance athletic performance with it oh hey you can if you're if you get fat adapted hey endurance athletics may be particularly beneficial if you're running your body off of ketones and the point is that if you take a ketone supplement you can get your ketone levels much higher much faster so the fastest natural way to do it is fasting but if you take a key to Nestor you're gonna get way higher you know like right away almost so is there some benefit to that and increasingly a lot of evidence says yes there could be some potential benefits to it because some cells perhaps run a lot better and of course the brain is one of these areas that has been studied a lot and I think it's a lot of doctors are sort of they stick to the you know prescribe script sort of thing and it's very interesting because the ketogenic diet was originally described like hundreds like a hundred years ago as a treatment for seizures and then it got lost with the development of medications and it took not a doctor but a film producer or you know this is the story of the Charlie Foundation surveys the son of famous Hollywood producer had intractable seizures nothing worked none of the meds working and all the best you know doctors and it took him researching the archives to find that this ketogenic diet would reduce seizures so he tried on a son and boom like the wall his seizures went away and it's like okay that's a great story why were the doctors not the ones to do this because they knew about it a hundred years ago and then they totally forgot about it and it's like it takes a holiday sir to tell you how to do your job like are you kidding me and I always think that it's very instructive because a lot of these things get met with skepticism by the sort of doctors the sort of mainstream medicine professionals but it's like when it works it works then your job is to understand why it works and ketones falls into that range where maybe there's some benefits to doing it but if it works don't just say oh that's quackery because that's what everybody says oh I mean I got my fair share of that oh fasting that's just a curry now it's like oh you know yeah yeah they're like of course it worked you're not eating so your blood Sugar's will go down it's like that's not what you said four years ago five years ago you said that'll never work you're a quack like but if you don't eat you'll lose weight they're like no you won't like are you not gonna lose weight yeah but this is the same thing with ketones that we see in that study what you see is that there's a benefit to the ketones in terms of reducing the blood glucose and of course this is one of the areas that I'm very sort of passionate about which is type 2 diabetes and hey is there a benefit there it's like so it's very preliminary obviously but maybe you can use it as an adjunct in some way maybe you can use it in conjunction with the ketogenic diet or conjunction with fasting or some of these dietary mechanisms or even with your regular medications and maybe you can lower the blood glucose and is there a benefit so maybe the answer is yes we don't know all we can say is that it's while studying yeah the other thing that I think is very interesting about exogenous ketones and type 2 diabetics anyway is that you can measure this ketone to glucose index so as your blood glucose Falls your ketone should rise because your body is essentially switching over from burning glucose to burning ketones and burning fat well if this doesn't always happen in type 2 diabetics so if your glucose Falls your ketones don't rise a shot yeah exactly so you got no glucose got no ketones you're just feeling like crap now if you stick it out long enough your body will eventually produce ketones because it's not gonna die but in the meantime it's not as easy as it could be and we've studied this we know that this sort of glucose ketone index exists and that there are different slopes for different people so normal people glucose down ketones up to diabetics a lot of them glucose down ketones not up so what do you do well that's where exogenous ketones could have a benefit maybe if you define the proper place to use it you could say okay well we'll give them ketones until they get into that ketotic state themself and then they're gonna drive obviously produce it yeah yeah because they can't endogenously produced it because it's great if you do endogenous ketones that's the whole point but what if you can't then exogenous ketones is a great solution so maybe and again more research is going to have to be done to sort of to find the best sort of solution to this thing but here's here's something that would be very very interesting to look at and potentially consider and you could definitely mix it up so if you're trying to get into that katatak state but you're falling into this low energy state where you have no glucose no ketones you can bridge it with exhaustion it's ketones until about fasting kind of kicks in and you produce and dodging is ketones that's okay that'd be great solution then you can get into there then you can start start getting better from the diabetes and stuff yeah so many possibilities here and I think that that paper was just a you know a great first lap saying yeah yes I agree I agree I mean we got to send you a couple cases so you can you know start experimenting if there's a way to publish some of the results I mean I think that's just how progress is done yeah I know I appreciate your perspective there as you know someone who's looked at it clinically across you know all types of interventions so the last topic I want to talk about was diabetes code so Oh piece of code awesome book it was one of the key books that I had read to get really ramped up into this space yeah well you know what are the new grounds that your planet cover so that book comes out in April right it's in about an April yes in about a month so the Addai abuse code is very specific towards type 2 diabetes and it's it's important for a lot of people because if you look at the population of the United States the adult population it's about 14 or 15 percent type 2 diabetes and about 38 percent pre-diabetic yeah almost actually a little bit over 50 percent pre-diabetic or diabetic so it actually affects a huge number 100 million plus people yeah it's one of these exams that people like or don't understand it's it's crazy and one of the things the the main thing that we talk about is that this is a reversible disease so everybody tries to convince you that it's a chronic and progressive disease that you've got it you're gonna have it for the rest of your life but it's actually not true you can actually reverse it and we see that with studies of say bariatric surgery where they do stop weight loss surgery when you lose the way the diabetes just go away and what I do in the book is really present sort of paradigm of diabetes of thinking about type 2 diabetes and the the easy way to think about type 2 diabetes is like it's like you think of your body as a sugar bowl your body actually just has too much sugar that's the whole disease if you have too much sugar your bowl is full and then when you eat all that sugar spills out into the blood so insulin which is the sort of a standard medication for type 2 diabetes does not get rid of that sugar what it does is it takes the sugar that's in the blood and rams it back into your body it's like oh okay well your body takes it because it's forced to but then it's just cakes getting more and more stuffed with sugar so then eventually that insulin that you're using is not enough to cram the sugar into the body and you're more insulin that's what you do so what we've done is give more more insulin and then because the medical treatment doesn't work because you never treated the underlying cause we say it's chronic and progressive and why do we dr. sands chronic and progressive it's actually because doctors simply cannot admit to themselves that their treatment is so spectacularly wrong because think about it this way you're an endocrinologist you spent sort of 20 years in the field treating type 2 diabetes and under your watch like 98% of type 2 diabetics have gotten worse you know they're getting worse because you're increasing the medication so you can either say say one this is a reversible disease therefore so if you put two Fox together one it's a reversible disease we know it for a fact is when people lose weight the diabetes goes away to almost all my patients are getting worse the only conclusion you can draw from that fact is that you're a bad doctor yeah you don't know what the hell you're doing right because it's reversible but your patients are getting worse you're you're not doing a good job as a doctor you can't face that you can't face that you have no idea what the hell you're doing right so then therefore you have to change the fact that it's not reversible it's chronic and progressive and I'm doing the best that I can it's like aging you might want to get young but there's no way you always get older 90 diabetes you say it's the same thing but it's not true and that's the problem is it's not true and it's a reversible disease and it comes down to this what we did was we took a disease that's essentially a dietary disease and we gave a lot of drugs and then we wonder why isn't your diabetes getting better because we're giving you drugs to treat the blood glucose but here's a thing we're giving all these are so focused on treating the blood glucose that we forgot to treat the diabetes you give insulin are they gonna lose weight no the answer is they're gonna gain weight so how is that gonna make their diabetes better it's not it's gonna make it worse it's a band-aid it's a band-aid because you've put a band-aid over a bullet hole right then you can't see it and you pretend that you're better so these drugs are essentially placebos for doctors they make the doctor feel good but they don't do anything for the patients and that's the problem but it's such a simple thing you got if it's a dietary problem you got to use your diet to fix it and here we have a solution intermittent fasting or extended fasting where it's completely free it's available to everybody like tomorrow and anybody in the world can do it at any time right and you're gonna save money you're gonna you're gonna make your diabetes better and think about it if you don't eat your blood Sugar's will drop well hey if you let your just drop don't you don't need that insulin anymore yeah but what you're doing of course if you think about that Sugar Bowl if you're letting your body burn down all that sugar and the sugar now when the sugar comes in it just doesn't spill out anymore but it's a hundred percent natural solution is it fun no it's not fun we bag we beg people to do it we Club them over their way you know we threaten them we yell at them we do what it needs to do but in the end what we're doing is we're trying to take advantage of the body sort of own ability to heal itself instead of giving pills right and that's where it's really powerful and that's where we created this sort of intensive dietary management program the website is IDM program com where you can get somebody to help you with your fasting but I'm in group situations where you can get support we do have this membership site which you can join for a lower monthly fee which is not personalized but you can get things like group fast which is just like what you do with the Wii fast which is where you have somebody and it will say okay everybody we're gonna fact that these days yeah you know who's in sort of thing and we'll have you know tips on fasting and recipes for not fasting all this kind of stuff but at the same time is all dietary stuff we're not trying to give people medications we're trying to take that medications away so it's here we're like you know we we can save people all this money like even if you don't care about your house if you don't have to buy that insulin you're gonna save a lot of money and two insurance companies hey your patients are gonna get better and you're not gonna have to spend all that money on health everybody wins except for the insulin producers no I mean III agree 100 cent with you I mean I think just seeing the stories in we fast and just people literally getting off of insulin through fasting and diet it's like and you know you know dr. Manny Lam that you know we work closely with I know that you know works with you as well I mean you know he's taking people through fasting and diet protocols and taking people off their metformin and insulin it's just like okay like something is working here and that way I think about it is that like you talked about it being hard it's like Oh exercise is hard – right like if you've never worked on your life it sucks but like we all know it's helpful for us to do some workouts I think the same thing will will change with the culture with fasting yeah the first time you fast gonna suck because it's like working out your your liver and you know whatever it's working out your body to go into a fasted state but you get used to it it's it's healthy long term yeah it's it's what you need to do to get better and that's what I always say like I get this pushback a lot from people are like yeah we understand why it's good but people will never do it I'm like I'm a doctor my job is not to tell you what you can and cannot do my job is to tell you what you need to do to get healthy and if fasting is what you need to get healthy then I will do whatever I can to support you through it and we'll create the fasting T and we'll create the IDM program to help you and we'll create these support groups like we fast well create these ketones that maybe help you get through the tough areas but that's the point is like we're helping you we're not we're on the same team here we're not trying you know we're not at cross-purposes we'll help you do what we can we'll do what we can and you do what you can and maybe together we can get you healthy I'm not gonna tell you you can't fast because I don't think you have the willpower that's like it's such a defeatist attitude it's terrible and you see it all the time and and again it's just like your grip is like when you tell people that it's great hey all of a sudden you get you know 20,000 people when when you start showing it on online it's talking to some I uh yesterday and it's like all of a sudden you're on the Today Show and people are like wow this is really interesting it's like well these are not new ideas yes sir ideas that have come sort of from the mists of time yeah people have been doing this for thousands of years the three most influential people in the history of the world the Prophet Muhammad Jesus Christ and Buddha all told their parishioners to fast not because they wanted to kill them because they knew that there was sort of something intrinsically healthy about once in a while letting your body clean itself out of all this extra junk that's accumulating and and that goes for it not just the glucose but also the excess protein that's accumulating and that's what it's hoffa G is you're breaking down these sort of sub cellular components this old junky protein and trying to replace it with something newer and better can it prevent cancer potentially I mean you know that the World Health Organization now labels 40% of cancers as obesity related hmm it's like here we pretend that cancer is a genetic disease it's like it can't be genetic because obesity accounts for 40% of the cancer so breast cancer for example is very highly related to obesity so therefore it's not genetic it's related to the obesity renewable theory of cancer yeah the work there is I mean there's so much interesting things about that you know this whole thing and we think about cancer in this way but say you turn down and this gets into these sort of nutrient sensors which is another sort of fascinating because our all these or ampk and insulin so there's there's your body actually is very very interested in knowing if you have access to food because if you don't have access to your body does not want to grow so nutrient sensors and growth pathways are very very tightly linked and you see this in the ovary as well so you for polycystic ovary syndrome for example you can treat it very easily by lowering insulin but the ovary has insulin receptors why because the ovary wants to know that there is lots of nutrients available before it ovulates produces an egg that can potentially become a fetus and a baby you do not want to be in the middle of a famine and producing eggs that can become a baby you're going to kill the mother which is gonna kill the baby because you have to divert resources into growing this fetus so the ovary is very interested in knowing if there's available nutrients so one of the things that the body has is several nutrient sensors so there's insulin so when you eat insulin goes up so that's a nutrient sensor mTOR is the one for protein and there's one called AMPK which is sort of this fuel gauge of the body so it's a reverse fuel gauge so when it's high it means your energy stores cellular energy stores are low so it's a fuel gauge whit's reverse if your ampk is low it means your energy stores are high and this is why a lot of people take metformin because it activates ampk and so it tells your body that is in a low energy state which is actually helpful for you which actually may help prevent cancer so there's a few studies that say well metformin can help protect against cancer and it's like why because it lowers AMPK and it's a very interesting sort of idea because again if you turn down if the body is not sensing any nutrients it is going to turn down the growth pathways and the things that are growing the fastest are those cancer cells but also for things like polycystic kidney disease i had this lady once who has very interested they had a hemangioma and what those are hemangiomas are these little benign tumors of the kidney anyway their blood and they bleed a lot so she actually had to get one whole kidney sort of resected because it was bleeding so much she would have bled out and they had to embolize to other hemangiomas which means they they they clawed off and clawed it off and burning it off yeah it's like burn so anyway a few years ago she decided that she's gonna do intermittent fasting instead so what's fascinating is that if you do this fasting she's her ultrasound measured a few times and on each one they say well it looks like the hemangioma is getting smaller but we know that never happened so it might just be yeah she's had like four that have shown that it's it's shrinking in size like fantastic because we understand what's happening you're eating zero so you're turning down all your nutrients sensor you're turning down your insulin you're turning down your mTOR and you're raising your ampk ketogenic diets are not going to do that they're only going to turn down your insulin but they're not going to affect am peaking and not going to affect mTOR therefore fasting is a much more powerful way to turn down your nutrient sensors the body senses there's no nutrients turns down the growth pathways which affects the hemangioma much more than affects other cells yeah so then all of a sudden you get this shrinking of this it's a benign tumor but this Imagi mode this benign tumor and all of a sudden she hasn't bled for you know the last year and a half it's fantastic and it's like wow the power of that is simply amazing because it's free and it's available and hey you might lose some pounds you might reverse your diabetes on the same breath and you may prevent the Alzheimer's disease so again Alzheimer's disease is this clogging up of your brain with all this excess Android like protein exactly so what if you could activate your body to break down all this protein intermittent fasting it's like whoa this is amazing right I'm toward goes down all of a sudden you stimulate at off a G and you're breaking down protein one of the interesting theories around it as well is that something that we're looking at is that you know perhaps Alzheimer's has a nickname of type 3 diabetes it's a glucose to uptake dysfunction in neurons if you can feed it ketones can you rescue some function and help clear out some of the talent amyloid which is related to you know some of the similar patterns you're talking about but but I think you know mTOR NPK insulin are some of the most targeted targets for drug and food so I think it is very cool that we can activate them in the right ways and the right levers with fasting I mean yeah in Silicon Valley people are looking at form in rapamycin which is yeah target for mTOR as you know potentially longevity hack so I mean like those might have you know additive or adjunct effects on top of fasting but it's it's all within that related ecosystem how do we it's all in that well in longevity yeah exactly how are we gonna aim crease longevity I think ampk a key plays a big role in that yeah but what's interesting of course is that you can target it with metformin you can target but you're not gonna turn down your insulin if you eat metformin you're gonna target the NPK if you rapamycin you can target mTOR you're not gonna affect the other pathways so fasting actually simultaneously affects all three pathways right it's like wow that's way more powerful and it's natural and then you go back and say hey you know let's look at these wellness practices for the last two 3,000 years right what do people say oh hey you should fast once in a while you go back to Hippocrates you go back to Benjamin Franklin you know Mark Twain they're like oh the best of all medicine is resting and fasting that's that that was this quote it's like whoa people understood this thousands of years ago that yes if you want to be well you should fast once in a while and it's like oh they were totally right like we think oh yeah I'm gonna if you want to be well I'm gonna take some rapamycin and metformin and like okay well I think you're gonna be better off with the other guy with you know Benjamin Franklin who is fasting because you're gonna affect all of the pathways at the same time and do it naturally rather than in a sort of this artificial way because you can you can turn down sensors and stuff it's hard to inhibit them long-term and it's hard to inhibit them completely in this sort of thing yeah I don't mean as a magic calm sellout because like it's human biology it's a complex system you know you can't just like push one pathway everything else is just like you know work magically yeah I think it's like these are interesting levers and I think intermittent fasting is one of these things that like just happens to touch a lot of them in the right way in a way that's natural that's this part of evolution right like you're designed to go through fasting and famine psyche or feasting and fasting cycles and it's been conserved throughout you know C elegans rats Mouse yeah yeah data just like that is the data is good because if you look at a NPK and M torso insulin is actually the most recent of the nutrient sensors mTOR goes way back and AMPK goes way back there conserved from you know there's nematodes right the C elegans and the Joseph Ilya the Flies and stuff you can find them in like every form of life it's like wow these things are like essential for life and thousands of years ago humans figured out a way that would actually help help help extend their lives so it's like wow this is just super super fascinating as a topic from an evolutionary standpoint you know how are we gonna do it how are we gonna use it to kind of hack our life right we're all talking about bio hacks and stuff and it started like the ultimate biohack I mean it's natural it's free it's available we just need the knowledge and the acceptance and people can tap into all these sort of superpowers in terms of health and wellness absolutely yeah let's build up the culture here so a lot on your plate so you got the the fasting T in June you got the book diabetes code in April any well anything else in the pipeline like what what's what's the future I mean I'm sure we'll have a conversation and have you again on the podcast hopefully not another two years but you know what what's what's next as you're looking forward well I'm working on a couple of things like obviously we've done the books and we've also built up the IDM program to actually be a solution for people to actually get some help so it's a program is the online program but then people can get help with their fast and get help with their diet and so on so that's that's something that we're working on building up and trying to roll out so that people can benefit excuse me so it's that's IDM program comm then I'm working on a book on PCOS which is polycystic ovary syndrome and reason I'm doing that is one of our IDM partners is dr. Nadia guano who is very sort of passionate about this and the reason she is is because PCOS is also a disease of hyperinsulinemia therefore as a disease of hyperinsulinemia fasting in the carbon diets worked very well but what we have is PCOS which affects somewhere around 10% of the target sort of women in the adult women and one of the big problems with PCOS is infertility spending like tens of thousands of dollars like a lot of money because they're infertile because of this PCOS and yet it's so easy to treat it's crazy that we could save that and you know I have two kids and I know it's like it's it's it's incredible to have kids then they become a pain in the ass but before that it's incredible but it's it's incredible to be able to give somebody that sort of gift because you know it's sort of so intrinsically human to want to have a family to want to have a big family if you can't have that it's like it's like an amputation it's like having your leg cut off like people want to have family people want to have kids and to have to spend ten thousand dollars a shot sort of ride in vitro fertilization is ridiculous because PCOS is treatable so easy so that's one one of the things I'm working on it and in the longer term so you know I get asked to write a lot of stuff but what I really want to write is about stuff that can make a difference to people and where I can bring something new to it so something like PCOS there's just not not any information so though these pseudo-code there's just not a lot of information type-2 diabetes reversal not a lot of information right to fasting there's a lot of information and PCOS and then the longer term maybe some cookbooks that will help people and then eventually a book on cancer which is again really really fascinating from answer code there's a lot there's a lot going right now the PCOS is a lot easier because cancer is not simply about obesity it's actually a lot more than that it's a lot it's it's about it's about a lot of these so many ideologies to I mean it just it just it's like a bunch of micro diseases in a fella term essentially it's way I cut thing about it yeah I think cancer is comes down to it's a I think it's about the mitochondrial disease it's a it's about all those nutrient sensors we talked about but it's also about apoptosis and esophageal ah'd of topics that get in there and it needs to be worked out a little bit better but there's some super interesting theories so we had this sort of genetic theory of OPC that was like crap it was like terrible and that's how you know cancer medicine is like the worst of the world like look at the progress so Nixon declared war on cancer in 1971 if you look at sort of the the rates of cancer now they're both the same as 1971 it's hard billions of dollars have been spent I know how many walks for cancer how many pink ribbons like there is so much money going to this that has done absolutely nothing it's like as if you you know with your iPhone you know in 2018 we're still using those giant you know vacuum tube sized computers that's the equivalent how can you make so little progress in cancer despite the billions of dollars probably trillions of good at for us like they're good people want to do good it's not like people are just wasting money I think people are earnestly trying to solve this problem oh absolutely I think started off on the wrong foot which is that this is a genetic disease and when you start off it's like if you're trying to go south but you start off by going north it doesn't matter how fast you run you're never going to get to where you're going yeah and that's the thing we started off looking at it as a genetic problem and we kept going and it was a disaster this whole Cancer Genome Atlas totally like tells us that we went in the wrong direction for 50 years and it's like and people still want to go in that direction because they've built their careers on it and if you don't recognize your mistake and start going in the right direction then you're never gonna get there and that's the real problem with cancer it's a much more complicated topic than simply obesity type 2 diabetes sort of thing and it's not simply fasting this you know fasting is gonna play a role but there's all this other stuff that goes into it so that's that that's the this may be the long long term it's but it's a it's a real interest of mine I think sort of to the bottom of what causes cancer what cancer is and trying to change the paradigm of thinking of what cancer is which is not a genetic disease 100% no appreciate I mean I like that you're still saying ambitious and pushing forward I mean I think in the last couple of years I mean I think we've just seen the community and interest and the and really the scientists grow so I'm just excited to see what you know yourself our communities can continue to do to I think really help people live better healthier lives so thank you for taking the time dr. Fung and we'll talk soon okay thanks Jeff and before I sign off here we're doing something new we've created a new email podcast at hvm ENCOM podcast at human calm to be our source of collating all your feedback for our podcast so send any requests for guests podcast ideas or feedback for myself ins ill will read every single one of your emails so again podcast at human comm podcast at hvm and calm and one last thing we're doing something new starting this week we're gonna give away a sprint mini for every single customer that leaves a review on iTunes so leave a review on iTunes take a screenshot of that and email us with that screenshot a podcast at human comm and for all the customers in the US we're gonna send you a free spirit mini as a token of appreciation for your support for our program so high level in conclusion podcasts of HP MN calm leave in iTunes review and then from there we'll send you a sprint mini as a token of appreciation

38 comments

  1. What if there was a way to multiply the benefits of intermittent fasting while also making it easier to accomplish?

    HVMN Fasting Aid replenishes the electrolytes you use while you fast and helps suppress appetite. It contains polyphenols including green tea catechins & resveratrol, promoting the natural autophagy and cell-longevity benefits of fasting. Try it out here: www.hvmn.com/pod

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  2. Thank you both for educating us and making it available for us.
    It is truly life changing.
    I'm an IF and keto promoter
    almost 22 kg down in 5 months
    thank you Dr Fung

  3. What is very touching is that obviously Dr Fung is doing all that because he has a lot of compassion for his patients.

  4. By doing IF in 3 weeks I lost 15 lbs and my A1c went down from 7 to 5.8..Im off also with my statin when I visited my doctor.

  5. I’m on day 4 of a 10 day fast and I feel great. So far I’ve lost 7 pounds. I don’t even feel hungry at all. All I drink is water, sea salt water, mineral water and unsweetened tea. I always thought that not eating would make me faint but that’s not the case at all. I have also been walking for an hour every morning and I’m amazed at the fasting results. You should try an extended fast to reach your goal faster. I have 47 pounds to lose, my goal weight is 135 lbs. I wish someone would have told me about fasting sooner. I have saved so much time and money by fasting. Please spread the word people!

  6. Your Chanel is awesome thank you . I wish you the best. Thanks again for putting in content that are easily ready available and so important.

  7. I wish that the interviewer would use a headset like Dr. Fung. He moves around so much that the audio varies to the point of distraction. If not, audio can be normalized when editing. Dr Fung applies scientific common sense to help people control their own lives. Thank you.

  8. So true doctors give you insulin but that keeps the fat on you instead of them telling people to watch what they eat they give them a pill or start them on insulin I gained 50 lbs fro. Steriods and 2 types of insulin and it's so hard to lose it so now I'm doing keto and i dropped my fast acting insulin now the long lasting i was on 34 in the am and 46 pm dosge now im 28 and 28 sometime lower if my sugar goes to low

  9. Love this, I've said for years the only reason chemotherapy works might work at times is because it makes the patient not want to eat!!!

  10. I like to say thankyou to dr jason fung may god bless you always.
    Just a month a ago i was told by dr that am diabetic so i started your intermittent fasting 19 20 hours everyday eating once a day only feel great my results in one month from hib test 50 its droped to 35.am amazed by the results.

    I used to feel dizzy out of energy always but with this fasting i feel great.
    Thank you so much.i would recommend your books to everyone very helpful.

  11. I've been fasting for a while now. Primarily for better skills at stock trading. But I can now see wide range of benefits and I had no idea I was so unhealthy until I started feeling the results.

  12. Hello Dr Fung, can't kidney transplant patients do keto and fasting? My kidney failure was from renal reflux that went undetected most of my life, so I had chronic infections that damaged my kidneys. I didn't have diabetes nor do I have it now. I had my kidney transplant almost 13 years ago. I am NOT on prednisone for rejecting, but I need to loss about 50 pounds and heal my depression.

  13. Dr Fung has become a super hero for pre diabetics. He has made it so easy to understand which is motivating. I was never diagnosed, but always worried about diabetes because my mother and brother were diagnosed.
    Can we refer to Dr Jason Fung as Professor X

  14. I have been on intermittent fasting for 3 months already. I have also given up carbohydrates in my diet; absolutely no carbs in it. And i am now down to 170lbs from 195 lbs 3 months ago. My problem is my fasting blood glucose still reaches 120, 121, 117 etc. It never gets to normal. But as the day progresses my blood glucose tapers until it turns normal. How can i bring down my fasting blood glucose? Am I diabetic? I would certainly appreciate your answers. Thanks in advance. By the way I am 51 incase age is material.

  15. GREAT podcast. LOVE Jason Fung!!..Please research and consider having Dr. Joel Wallach on your program as well. His knowledge on longevity and repair of all body cells is brilliant!! Some of his more notable successes include:
    Evander Holyfield.. 
        Fighter….rebuilt heart
    Theo Ratliff..basketball..Bone
        to bone Arthritis…rebuilt
        knees
    DeLisha Jones
        basketball..rebuilt her
        joints, connective tissues
    Loretta Scott King…knees
        rebuilt
    Nelson Mandella…Lived so long
       and healthfully while in jail
    Creflo Dolar's daughter's
       asthema cured in 7 days
       (Unresponsive to medical
        treatment, was hospitalized)
    Andrew Young,(Jimmy Carter's
         UN ambassador) scheduled
         for double knee
         replacement, rebuilt knees
    Drew Pearson, rebuilt shoulder
         + back
    Kelly Haren, rotator cuff
          rebuilt
    Fred Glass, powerlifter, rebuilt
          his bone + joints
    Danny Glover, back & hip
          problems, rebuilt him, now
          back to strenuous movie
          schedule.
    Pat Boone, back & joint
          problems, now back to full
          entertainment schedule

    Thank you for your hard work and informative podcasts….Blessings..

  16. Do you suggest a particular supplemental exogenous ketone ester until endogenous ketones kick in while trying to reverse T2DM?

  17. Wow, amazing video. I have started following you recently. I come orthodox Indian family, in my life I never had breakfast. When going to school we use to drink lemon water and then lunch and dinner. That's the reason no one is obese or diabetic in my family. We never did any keto. Our food is rice and flat bread with heaps of vegetables. Though I am vegan I never had any protein deficiency problem. Never had supplements in life. Thanks to my grandma , she thought us to fast every 15 days once (water fast) as it is traditional . Thanks doctor for sharing immense knowledge.

  18. Cancer is big business. The will never be a"cure" because treating it is big money. No money in a "cure". A shame…really..

  19. As a health care professional and dentist I kept raising my insulin daily dose and subsequently weight. Should have known better than follow all my endocrinologist advice. He did say if I lose 40 lbs I can get off most of my meds. Not taken seriously enough! I'm 72 years old, still practicing and not ready to die yet. Dr. Fung's on- line discussions gave me enough inventive to turn dietary habits around and hopefully eliminate type 2 diabetes with my spouse, diebetic as well. She also uses metformin and no insulin with better readings than me. Thanks for the mental support! Dr.D

  20. Love you Dr! Keep up the amazing work and may God bless you. Best wishes to everyone trying to lose weight and make good changes for better health! Happy fasting!

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