The Experimental Ketamine Cure for Depression

Oh [Music] [Music] Oh [Music] my name is Steven Grissom born and raised in New Jersey going on I was jumpy deaf kid short short us a bunch my dad you know he wasn’t around my mom would single mom she had seen three jobs at some point and and I couldn’t hear a lot of the conversations growing up cuz I’m deaf so it kind of kept me on the outer skirts of social circles or whatever all that stuff it really affects you Rhona and you know keeping it in was probably my worst mistake I wish now that I would have talked about any of this I don’t like they eat you alive it should do you feel like there’s no other option but to say this is it I can’t take it my warm I tried going to doctor they had prescribed me some pills wasn’t doing anything so I suppose forget it and now I’m doing ketamine treatment millions of Americans suffer from depression and many of them don’t respond to traditional treatments like antidepressants what was once known as an animal tranquilizer and even a party drug is now proving to be an effective treatment Steven Gracie is 28 and he’s been suffering from depression for most of his life okay hey what’s up you know it’s going on Bioman good to see you thanks man thanks man over in your head is there a piece of your life before ketamine treatment and it fades after a tried to ditional doctor you know you know going on like a couple pills from my anxiety and stuff I didn’t like it I didn’t like what it did and how it made me so what what did it do how to because I just felt sick to my stomach all the time it was just like I’m not going to do this and there’s got to be some other way to do it a year ago what was an average day like for you dealing with depression that’s normal for someone to be depressed but it it’s how deep that depression goes and where that depression came from for me it’s come from my childhood I mean you know who how do you tell your parents that you were raped you know I’m 12 13 years old what am I going to do shut down everything from that moment on which sucked away from me so yeah every day every day I wake up and something is wrong something going to go wrong this is going to happen that you know every single day but the difference now is I don’t let it overtake me I don’t shut down instead of me being suicidal or thinking of the chassadim I have to strive to deal with it in some shape or form once I had the first three or four or five treatment that motivation to stay alive that motivation to move and do things to get things done came to life I’m here at the ketamine treatment center of Princeton New Jersey and this is where psychiatrist dr. Steven Levine has been treating patients since 2011 he typically sees 10 to 12 patients today and today steven is going to be receiving a ketamine infusion what exactly is ketamine doing in your brain in your body so most of the focus has been on its effects and what’s called the glutamate system ketamine can produce these proteins that repair connections help form new ones reroute around areas of damage it’s a process called synaptic plasticity so that’s one thing that ketamine does and that’s part perhaps is how it treats depression there’s also the experience during ketamine and I think we generally devalue experiential treatments or how experiences change us and for some people that may be very important so how you doing doing good doing good little overdue and I’m the last couple days definitely good to be back here and get my infusion you know the thoughts on your mind right now or questions as far as looking forward I think the only concern is just how long you know what I do two treatments I think we’re on 14 15 no I think it was number 14 14 today so I thought I was going to be done it like five or eight you know so I guess I get fearful that you know they decide that ketamine is destroying the world one day that ear practices would go out then what do I do you know I mean because it tells me so I obviously want to continue yeah so I guess there’s two domains with that but if there’s the course of your own treatment in the near term and more distant term and then there’s what’s going to be the ultimate fate of the use of ketamine for depression and if this type of use this ketamine for you of course one of the things that we’re trying to do over the near term is is to have you kind of feel like you’re failing on your own that this treatment is there for you as a backup if you need it right yeah Kaddi me like anything else is in a magic bullet I never think of time right the answer I guess a tool all right absolutely well not one tool works for everybody so exactly so Steven would you say that you actually enjoy undergoing the treatment not when you’re getting stuff is great I do enjoy it it’s like it’s not frightening like I said it’s it’s pure solitude I’m able to analyze myself I’m gonna let go boom yeah I do enjoy it you know I think that’s why I keep coming back because you’re you believe that it does give me it’s slowly seeping in farther and farther sure my scope dolphin yeah my hearty yeah my speech might just be a little weird so I’ll go let me know where you want me to leave you no no no you’re cool you’re cool vehicle what’s your feeling now is compared to the first couple times you got Academy infusion their first couple of treatments I had were yeah I’m not I don’t think I’ll be able to answer that yeah it’s there yeah yeah come here guys okay cool I’ll leave you to it then then and yeah I’ll catch up with you after the treat and again face like there’s a number of existing treatments for depression for chronic depression what are those exactly and how effective are they so most currently available treatment for depression if we’re thinking about medication so mostly based upon what’s called the serotonin hypothesis of depression and the idea that you don’t have enough serotonin and you don’t have enough of these feel-good hormones in the brain and if you replace them with medicines that increase those levels you feel better and they work moderately well but when I read the early papers on ketamine there’s only been a few studies at that point back in 2010 when I read those studies they spun my head around because they were unique in some very important ways and the results were dramatic that made me wonder why aren’t we using this we wanted to get an alternative opinion on the effectiveness of ketamine infusion treatment so we’re here at Yale University to meet with dr. Stan Acorah he’s been working in psychiatry for 26 years and is knowledgeable on treatments for depression including ketamine generally speaking how safe is ketamine we know as an anaesthetic it’s considered to be one of the safest in fact there’s been hundreds of thousands millions of people that have been treated however in those cases it’s usually a single dose given one time here it’s a little different for depression because we’re giving it repeatedly over and over and over or at least it looks like that’s the way it’s going to be going if we want to maintain the response we don’t have very good what we would call prospective studies where we actually image somebody’s brain before they use ketamine for long periods of time and then image it again after and with that in mind what is the biggest red flag to yourself and other people in your profession when it comes to ketamine infusion treatment so I think the biggest concern that remains is we still don’t have great evidence that we can get somebody better and better but also in terms of the danger of it so we know that people with substance abuse disorders or substance use disorders that abuse ketamine at high levels there are several studies suggesting that high level use of ketamine is associated with cognitive deficits actually with changes in the brain structure some reduction in some of the frontal cortical mass and volume so your brain would actually deteriorate over well in Rosen studies we do see that it can cause some toxic effects on the brain and even at relatively modest doses even what we call sub anesthetic doses with repeated doses there is some evidence that it could cause some unwanted changes in brain structure from what we’ve learned so far the dosage is prescribed based on a person’s body weight and on not much else there’s not many other metrics that decide the amount of dosage that’s going to go into a person we really don’t have a good idea of what is the optimal dose or even how to decide on what those to give patients so that to me is probably the biggest concern is how do we know you know what is the right amount to give what is too much to give is there any right amount that’s safe and those are those are my biggest concerns from I’m treating patients and that’s what I always wonder about is we really don’t know how safe this is long term and we really don’t know how effect that this will be long-term [Music] over the last decade Stephens mother witnessed her son’s multiple suicide attempt but she has only recently learned about Stephens experimental treatment since he chose to keep it a secret due to the stigma around ketamine how did you feel when you first heard that Stephen was undergoing these treatments and then again you know when you found out that they were somewhat effective for him it’s scary I’m concerned it’s a drug that’s addictive but if it’s helping you anything that’s going to help my son is going to it’s going to be the best thing for him does it still scare you at all or you know after undergoing some treatments does it seem more like a treatment for what you have after the treatments my life kind of slows down I get to think about things a little bit more I don’t have to be so hyper about things and definitely without a doubt keeps the chatter the flashbacks just the morbid thoughts that I had away and that’s why I think I am more supportive because it helps me have a little bit more of a comfort knowing that that’s helping you function better as a person in society in terms of the other people in your family what do they know about Stephens depression and about the ketamine infusion even family members or judgmental and here’s my son and I want to do anything anything that if it helps my son of unported I may not understand it fully and I don’t care that I don’t I see the results and that’s what help although ketamine is fda-approved as an anesthetic it’s not approved as a psychiatric treatment which means that ketamine infusion therapy is not covered by most insurance companies so these ketamine treatments that you do here are not something that can be covered by most people’s insurance right yeah so most people do assume that they would not be able to get any insurance coverage for having ketamine treatment our patients who see us because all of our centers are run by psychiatrists people meet with psychiatrists before and after every treatment we are able to get people bills that reflect the psychiatry office visit component of their visit so while the ketamine infusion itself is not covered our care is and so it’s not a completely uncovered Service agent fusion costs even $450 he spent over six thousand dollars on treatment so far and doesn’t know how many more he’ll need how do you feel after that treatment huge difference yeah huge difference do you feel like you’re getting progressively better or is it like kind of big you’re now you’re anticipating your next treatment it’s getting better if I can do one infusion every thirty days instead of every three weeks I think that as an improvement and so what are you going to do now I mean that you weren’t able to do before you know on a Wednesday well whatever I want that’s the beauty of it I’m not incapacitated well I’m really happy you’re getting better man you know you’ve been through a lot of stuff you know really difficult times in your life and you found something that works for you and congrats on that man I’m really happy that we got told after talking to Stephen and hearing about his issues and how ketamine infusion treatments have helped them I also discovered that there’s a number of depression and anxiety related illnesses that come from PTSD I actually myself was diagnosed with PTSD about ten years ago so I thought maybe I’ll try one of these ketamine infusion treatments here at dr. Levine’s office so dr. Levine this is a consultation you typically have with your patients when you’re assessing whether or not they should receive ketamine infusion treatments all right that’s right and so essentially I want to get a sense of you your story of you know why you might be coming in for treatment whether there’s appropriate indications to have this there’s any contraindications that would say we shouldn’t do this so in terms of considering having this treatment today can you tell me a bit about your experience you know I wouldn’t consider myself to be a depressed guy you know overall I think my moods are generally positive however I about ten years ago I was diagnosed with PTSD because of an incident where a mugger stabbed me in the throat my arm was paralyzed for a while and it’s something that I think I still feel anxious from it time if this is something that can help me dissociate from that post-traumatic stress I think that would be really helpful something I hear commonly from who have trauma who have this treatment is that oftentimes they’re able to step apart from themselves in a way that they’re able to look at their trauma in a more objective less emotional way which in some sense is like an advanced exposure therapy okay cool I think I’m ready all right let’s do it all right good all right now I’m going to put the ketamine in so you are all surrounding here it usually takes about 20 minutes or so before you start seeing on it okay all right yeah I’m good a little relaxed first or we’ll see we’ll see what happens [Music] so I’m definitely starting to feel some of the effects of the ketamine it’s making me a little bit drowsy and I feel kind of like a warm sensation you know behind my ears wow dude ya know it’s like it’s like a pretty pretty strong like psychoactive effect those day yeah well I’m pretty up usually at the 40-minute mark is when he’s at the height of this distribution the peak of it so you still have a little more go up the best thing to do is probably just keep your eyes closed and just try to relax and not talk through it oh now that might help that feels good now feels like it’s like really sounds like my toe the interesting thing is the uniformity between like the mental effect on the body effect or suffering this effect is actually doing something to your brain chemistry or to your body and that can actually help you to cope with the realities of life or whatever right the realization I’m having on this is that like that emotion doesn’t have like like physicality right in the world but there is a big difference between what’s tangible always been tangible it lets you kind of encapsulate all those things in your life right all your feelings your you know your relationship your upbringing all those other things like sort of all into one thing and you sort of set it over there and you’re just walking around you’re looking at them then you don’t have an emotional reaction or attachment or something from each image or each experience that you see imagine your life is a movie if you’re in that movie you’re just having the experience the whole time you’re that character who’s just like you know be swayed left and right by all the things that are happening in that story right but if you’re in the audience if you could watch your own movie alright if you can watch the movie of your life and judge every aspect of it right without any sort of emotional reaction that’s what discipline if I had gone through what even have gone through I can imagine that going through something like this just removing yourself from the perspective that’s so so damaged you know at some point you’re probably really helpful I think I’m beginning to perhaps understand you know what this does for your patients men that really is an incredible experience have you tried to just in general for like this was attic the experience you know like I just to look at my thoughts in a different way like that was so incredibly therapeutic men I’m pretty confident that ketamine treatment has contributed to me being here today a mass majority of this because even though you grow older and you get wiser there’s still that deep emptiness inside that like I couldn’t explain that bothers you and ruined you from inside and then just shut you down and I think because I’ve been able to subdue a lot of that and kill the chatter per se it’s allowed me to function and be more happy and not have to think like that actually patients suffering from depression or industry and unfortunately many of our treatments right now while quite effective for many people leaves about a third of the patients that really aren’t Eastern see tremendous benefit so there really is what we can write on vacation ketamine offers that hope to people I’ve seen my own patients several over the sedative change their life and life-saving so I don’t think it’s fair not to make this treatment available people on the flip side if we are going to offer this what’s offer it in safest setting you community in this responsible way for developing it and in a way where we’re learning from reflecting and sharing [Music] you

100 comments

  1. The FDA hasn't approved ketamine for psychiatric disorders — but that isn't stopping "off-label" treatment clinics from opening up all around the country.

    WATCH NEXT: The Cuban Punks Who Infected Themselves with HIV in Protest — http://bit.ly/2kXEa2N

  2. Please please please do a piece on the new nasal spray that’s ketamine based and got approved by the FDA. We need more awareness to make sure the people who need this treatment have access and can get the treatment covered by insurance.

  3. He’s obviously addicted to a drug lol look how he lights up when it’s treatment time then gets sad when they talk about taking it away and is a little bit manipulative on his answers obviously

  4. I am one of the several people who got depressed and it .
    happened to me years ago after divorce. an actual low point when I got this depression treatment method “fetching kafon press” (Google it) and my confidence was smashed. Within weeks of reading through your book and putting your advice into exercise, my depression had completely removed and my confidence began to come back..

  5. So They Give Folks Methadone, EVERY day. But They are "conserned" as soon as its mushrooms or ketamine. This is further proof that the state do not want your best. They want you obediant, and They want you to work, But They do NOT want your best OR tell the truth.

  6. Ketamine infusions helped me sooooooooo much! I participated in two drug trials for Esketamine. One was an I.V..infusion trial and the other one was a nasal spray. Definitely liked the I.V. trial better, the nasal spray made me feel really weird. Eventually though, the nasal spray worked quite well.

  7. If Big Brother change their obviously outdated beliefs and views on medicine like marijuana and psilocybin there would be far less people taking the very dangerous big pharma meds. Bit their pockets wouldn't be lined with so much lobbyist dollars. One man's honest opinion.

  8. 16:59 I thought they added that sound track of drops to simulate the IV , than I saw it was him making the noise, LOL

  9. People have been curing their own mental illnesses for centuries. It's only when government intervention and regulation come into play that people seek other means such as alcohol which exacerbate the issue.

  10. from someone who Knows of this treatment (my brother) and know of those who have trama, like this its best to just deal sometimes.

  11. ketamine is a crapy drug. Depression is just bordom. wa wa wa. There are two cures for "de
    pression" 1. get off your ass and stay so busy you dont have time to be depressed, or: just fucking commit suicide so we dont need to hear you whine.

  12. LOL that was a complete waste of time horrible documentary all the questions you have going in are still there at the end

  13. Here’s a bit of info on the current state of ketamine treatment. Ketamine infusions are close to being FDA approved and a version of ketamine called esketamine is now FDA approved. You don’t benefit instantly from your first infusion either. You go 2 to 3 times a week for a few weeks and slowly decrease frequency as it takes on a longer lasting effective treatment. People usually reach a point of going 1 to 3 times a month for infusions and on days you need a boost going and getting esketamine to hold you between infusions. I have been using ketamine on my own but produced in a pharmaceutical industry that was giving me medical grade ketamine to use on my own. Before ketamine, I was committed into hospitals multiple times a month for years. A year using ketamine has got me stabilized to the point I’ve only been committed one time in the past year. I use ketamine for ptsd, borderline personality disorder, severe anxiety, Parkinsonism, fibromyalgia, drug addiction, seizures, and chronic testicular pain. That’s to name a few of my diagnoses. A year into this, only negative side effect is with bladder. But I got hit by a truck 3 years ago that messed up my bladder and ketamine has only made it more difficult to ever empty my bladder than it was before ketamine. I have follow up test periodically to measure any negative effects and we just have to get my bladder to empty so it doesn’t cause life threatening infections. So all is going good this far. I switch from self medicating under doctor observation to the ketamine clinic this month. So far, basically zero health problems are manifesting and we are working on making my bladder back to proper health. Ketamine treatment saved my life. Used in closely monitored situations it’s very safe and effective. However, it’s a last line of treatment if all else fails. Don’t believe the stigma. I have a year of testing my body functions from ketamine use and virtually zero problems have manifested. They can fix my bladder and then I’ll have zero bladder issues and continue ketamine fine.

  14. Ketamine is approved for my condition for REFLUX SYNTHETIC DYSTROPHY/COMPLEX REGIONAL PAIN SYNDROME…. My pain beats cancer pain on the national pain scale, they offered me the ketamine injections…. I related them way too much to party drug users… I couldn’t do it…

  15. I would really be interested in trying this. I’ve always had depression, and I’ve never been motivated to do a single thing in my life. The only thing I live for now is to get high. It’s been that way for two years. That’s no way to live. Maybe if I understood my mind I wouldn’t be this way.

  16. God bless all the sad and brave souls that are sharing their hopes and stories and love here.
    I Love You all too! Stay strong and lets all keep fighting together. It doesn't have to be a perfect world, but its a lot cooler world with all of us in it!

  17. Ok but why did they let him drive off on his own after? My Dr. does not let me drive for 24hrs after a treatment.

  18. I've seen people on this treatment and it is true. It does damage the brain and for the overall long term. At least w my sister it did nothing to help w her depression. She also was a rape PTSD trauma victim

  19. I think I heard that Ketamine is now sold as a spray to people that are struggling with depression. Not sure if it was in Canada or USA though.

  20. Dear doc I’m gonna pay you for putting me in a K hole….. am I cured yet?

    Dear patient not until I pay off my second house…

  21. This treatment saved me. I didn't realize how really, really down and desperate I was. I knew I'd been depressed for basically my whole life. After the first treatment (I've had 6) I felt like a new person. I was a lighter, less weighted, less dread, less doom person. I actually have been waking up on m own, early, and not forcing myself back to sleep to escape. This one aspect, in and of itself, is amazing to me.

  22. the host seems like a moron..but other than that…it was interesting research..as i was curious how this particular drug was used to treat depression…

  23. Thanks for making this video y'all! This will definitely help me write my 10 page paper on the medicinal use of ketamine for treatment resistant depression.

  24. I was in two clinical drug trials for Ketamine for treatment-resistant depression and I can tell anyone, it works! I did the I.V. and the nasal inhaled trials.

  25. “i may not be safe or effective for a long period of time”
    well, neither as prescription drugs, my brain is fucked from antipsychotic’s and antidepressants.

  26. Wish I could afford this treatment. I'm only a half hour away from this facility and suffer from treatment resistant depression. Taken every pill under the sun and if one more fucking psychologist tells me to take a long walk and appreciate the surroundings i'm gonna punch him/her in the face.

  27. Everyone who thinks theyre anti-drug just isn't once they need to save a family member with it. I'll dose my own kids if they start attempting suicide, shiiiit

  28. What he said about watching a movie of your life from an outside, objective point of view when you're on Ketamine is so true.

    The last time I used any drug was a Ketamine analog called Deschloroketamine (DCK) over a year ago. I'm an alcoholic and a drug addict and it was a relapse. I had ordered drugs online and wandered off on a walk, away from my parents house and into the woods to go use them. The problem was for some reason, I had mixed up the amount of time a Ketamine trip takes with Nitrous….. I've used a lot of drugs in my life and never made a serious error in judgement like that before. So anyway, after awhile, I realized my mistake and that I wasn't going to be able to go home, because I was obviously tripping. Then my phone died.

    Long story short, my parents basically thought I had fallen off of a cliff in the woods and died. But seeing my life, my drug use, my recovery progression from an outside point of view was absolutely incredible. I remember saying over and over again, "I'm so fucked". It was extremely powerful. I credit my year in sobriety now to my strong support network within AA, friends, and family but I like to think that the fact that I had used Ketamine as my "last use", had something to do with it as well. It just gave me a whole new perspective.

  29. Cardio,going to the gym in general, mindfullness and understanding the physcology and bioligical reasons will make you alot better not taking ketamine this is such a far left treatment bet uni students love this😂

  30. I no there are no words that i can say to show how thankful i am to see the people trying this drug.. being a lab rat would not be fun. I may need ketamine in the days ahead but very scared to get it.. i wanna be sure that its safe long term. I don't want to be a pussy but i would rather die than forget everything and lose my mind, of course i already feel that way.. but thanks everyone it truly means so much to me. You people are very brave i no depression isn't fun i had it six months straight now and i couldnt imagin staying in that pain for as long as some of you.. i tempted suicide and was just put on paxil i hope it works for me.. God is looking out for us people. Also thanks for the researchers doing great testing..

  31. I couldn’t hear a lot of the conversations..because of I’m deaf
    Side note: I’m going to hell anyway

  32. I genuinely think that is curing his depression because its giving him something to look forward to

  33. I was stabbed in the neck some years ago, and so since then i get spells of anxiety and feeling associated with anxiety. It must be PTSD. Right Doc? So Dr. Feelgood I think can certainly benfit from the same ketamine treatmine that my buddy here just got. Do you agree dr.? Of course my son, you too can experience a better life through chemistry

  34. I have suffered with depression since I was 13 and now 32. Two years ago after I had a nervous breakdown I was diagnosed bipolar and PTSD. Lamictal was a life saver but after two years on it, I see it's starting to not help as it did. I see therapist and he doesn't help. He ask if I'm taking my meds and listens to what I have to say but never offers anymore help! They say this can cause long term affects on the brain. Coming from someone who struggles when it comes to how I think. We don't care about the long term affects because we are just trying to survive day to day! Just know you are not alone! I'm so sorry we suffer from this disease and pray for help!

  35. Of course the FDA won’t approve it b/c it actually works. Instead, let’s give you a shit ton of psych meds so Big Pharma can make a pretty penny. Then, those synthetic meds will give you side effects, and you’ll need more scripts. It’s insane how many people who are initially prescribed one medication are then given numerous scripts, and you come to a point when you’re just treating side effects to meds. It’s a vicious cycle.

  36. $450 per ketamine infusion!?!?!?! Wtf!?!? Some of it covered though right? LMFAO, and drug dealers are the criminals eh? SMH sad af really

  37. A bunch of Coca-Cola will try your brain. The repair of the synapse and dendrites interested sign me up. Chronic depression daily.

  38. The journalist is clueless. He didn't need it but did it to see how it felt. His experience is not like the experience of someone who has real depression or real PTSD.

  39. I'm in the same boat but cant afford a ketamine clinic . If anyone has some to sell let me know.

  40. If depression kept me down for YEARS and didn't do anything important because of it and then all of sudden I didn't feel that way I would probably feel a degree of rage, not relief. Rage at someone who was responsible for this unnecessary emotional pain and humiliation that comes with depression.
    There is no way to win once you are cursed with this horrible disease.

  41. I have been depressed and feeling worthless for SO LONG that I would not know how to handle success and the pleasure it would bring.
    It would most likely freak me out since, to me, it's not normal to feel good most of the time.
    I feel like the more successful you are in life the better the chance that you will be damned in the afterlife.
    I might be interpreting things wrong but I feel that way.

  42. This could turn into a "if you want your pleasure then line up and do as we say and pay up".
    This treatment could seriously turn into a horrible master/slave situation.

  43. The medical industry has a GOLD MINE in not curing or giving a concrete treatment for depression. The suffering of millions on ineffective, yet profitable anti-depressants would be undercut from any treatment that is simple and once a month.
    The system is more corrupt than you think. If you are weak and mentally unstable, God help you – they will crush and destroy your personality.
    It's almost as bad as the 1800s but in pill form.

  44. After watching this video i feel comfortable in saying that, as an Earth Born human being, having lived in 3 continents of the world throughout my life, I would honestly say that, beyond a shadow of a doubt, while also not intending to hurt anyones feelings or ruin anyones day just by commenting, and while still remembering that so many lives have been lost throughout history that were directly related to this subject, and also trying to be completely objective while still offering insight into the situation, I truly think that, even if you don't personally agree with me, and keeping in line with the narrative of this video, that i forgot what i was going to say.

  45. I got anxiety and depression.only realized after 5 months struggling. I feel useless, afraid of the dark, difficult to breath that led me to get out from the house to get oxygen, i throw all my ciggarettes, no mood, no appetite,keep on switching on and off tv, no interest, mind was at work, thinking of your boss keep on shouting angry at you, finding mistake,once or twice i got breathing difficulty and i rush out to open space outside office to get me to breath in, i cannot sleep..everytime i lay down on my bed,,i saw a huge crator underneath my bed, i feel wanna die, ended up crying and texting my lover telling that i dun feel good, scared. Went to see doctor and prescribe with flouxetines and xanax. BUT NOW, im getting stronger tha ever, i dod exercise regularly. Your experience taught you to become better and stronger person than ever. I hope i wont get to there anymore.its scary!!! Really

  46. My brother is trying this after trying everything else. I suffer from depression/anxiety etc. and I'm on disability and my meds are keeping me alive and sort of functioning. If I feel really bad I go get high on pot. He has never drank or done drugs (won't try pot until it's legal, which is happening soon in the state where he lives) and I mean i'm really scared because what if this doesn't work? Where do you go from this point? He's such a good guy, very lonely(like me) and he still works, I don't know how he does it. He's smart and funny and wouldn't hurt a fly. I visit him when I can but I don't know what to say to him anymore. The last time I saw him they were trying Ritalin on him and he seemed happier and upbeat but he said it started making him feel like he was going to have a heart attack. So he quit that. I've tried a similar drug for ADD and it helps mood and focus but after a while I crash and have had heart trouble with it and other meds. It's a shitty disease, and people don't get that it is a disease and not just a bad mood. I hope he feels better soon.

  47. The bad thing is that most people can't afford this treatment. That makes people have to continue to suffer. Not everyone is able!!!

  48. I’d be curious to see if this treatment reaps any benefits for people suffering with schizophrenia. My best friend’s older brother was diagnosed with it about 7 years ago and it’s heart breaking.

  49. Wow. The interviewer became extremely introspective and had a very mindful paradigm once he got the Ketamine infusion.

  50. All my life, I've struggled to fit in and one thing I want to address is that I don't blame society, as I blame myself for not recognizing my deficits. Sure, I was diagnosed with Non-Verbal Learning Disorder (Autism) when I was about 13, however, I never recognized until now that YOU are the one who controls your destiny. For example, my mother would often suggest that I write down a very specific schedule of what I want to accomplish each day, yet I didn't understand the context of what she was telling me. My mother would often suggest I develop hobbies and interests, but again it was something that I didn't think it would help due to the though process that it wouldn't help, but what I failed to recognize is the power of belief. Now, that I've finally recognized the error in which I've lived life I am now giving ketamine a try AND having the belief that it will help. This video has given me hope and I want acknowledge that I am truly thankful for this video.

  51. I think one thing we have to remember (which is often disregarded) is how important—in fact just as important as the treatment itself—the integration process is (the takeaways after the treatment). Dr. Levine made mention of the experiential significance of the treatment as well as the neurological adaptations taking place and, sure, some people's brains may produce less serotonin than others for whatever reason but the question is how did that come to be? Why are people suffering in the first place? What happened to them in their lives that reduced their self-worth, outlook, ability to assert themselves etc. The great thing about using ketamine (even without the drug i.e. meditation with an eye-mask) is that it promotes reflection in a safe-space. Ketamine enables a disassociation from the story the ego-mind constantly narrates. People come to a deeper self-understanding but those lessons—those downloads—MUST be integrated into life for positive change to occur. As Morpheus said to Neo, "There is a difference between knowing the path and walking the path." Great documentary though!

  52. I’ve had 21 ketamine infusions and I am doing better. I’ve managed to stay out of the hospital for a while. Earlier this year I had 8 hospitalizations because I attempted to ended my life multiple times. I’ve been out of the hospital for 8 weeks. I’m doing good. It’s the only thing thats helped me stay out of the hospital.

  53. As of March 6, 2019 the U.S. Food and Drug Administration "approved Spravato (esketamine) nasal spray, in conjunction with an oral antidepressant, for the treatment of depression in adults who have tried other antidepressant medicines but have not benefited from them (treatment-resistant depression)." https://www.fda.gov/news-events/press-announcements/fda-approves-new-nasal-spray-medication-treatment-resistant-depression-available-only-certified

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