Treating Autoimmune Disease – with Author Pamela Popper

well I am happy to be back and thank you so much for coming to listen to what I have to say today so I come from Columbus Ohio and I'm president and founder of wellness foreign health and our company specializes in informed medical decision making it's a practice specialty that we invented and I'll tell you what that means what that means is that consumers should buy health care the way they buy everything else I want you to think about this for a minute when you go to buy a car what do you do you check out online you do a lot you ask friends you look up warranties you do some research right in fact I've been in business for 22 years and I've never had somebody pull up in a new car into my parking lot and I said well you got a new car yeah I hate it but it's the salesman told me I had to drive it alright and how do you buy houses I mean do you just basically let the realtor choose do you say something like you're so much smarter than I am about real estate so you just pick out a house for me and tell me where it is show and I don't need to read those mortgage documents I mean that's that's crazy you guys know more than I do just tell me where I'm going to be living you know people invest more energy and researching before they buy a blender than before they have major surgery and this is a problem because when I'm open every afternoon for practice here's what I hear all the time if I had known then what I know now I never would have and you can fill in the blank all right so our business is helping people to look at the evidence filtering everything through a stated evidence filter we have 23 criteria by which we evaluate evidence and then people can look at diets supplements screening tests diagnostic tests drugs and procedures and decide on their own what's best for them and I tell people every day if you know doing informed decision-making isn't doing what I say even if you think I have better ideas it's doing what you think is right after you've looked at the evidence how many people think that that would lead to better health care and people would be happier about their choices if they knew what they were doing all right so now it's basically what we do and what we want to get people away from is if I knew then what I knew now and I'll tell you this very interesting thing about informed medical decision making it leads to a place that I think everybody here would like to see more of people decide to adopt a plant-based diet and I'll tell you why when you when somebody is has cardiovascular disease coronary artery disease we go right to the drug company's website and show them crusto will reduce your risk of a heart attack or stroke by 1.2 percent do you think most people know that they don't well you know that's this diet starts to look really really good the plant-based diet when you know that some of the drugs and procedures are not as effective as you might have thought so basically today what I'm going to do is I'm going to talk to you about autoimmune diseases and their causes it isn't just diet some other things too but you have to change your diet if you're going to recover or stop the progression of these diseases and then we'll have some time for Q&A one thing I'll mention a pairing this down was very difficult for me I teach a course through our school on autoimmune diseases that includes 24 hours of lectures and another 15 or 20 hours of lab discussion patient experience etc and so I had to condense that down into 90 minutes which means that I will have to talk very quickly all right so anyway let's go on ahead and get started so the first thing is like all diseases the incidence of autoimmune diseases is increasing not decreasing eight percent of Americans have been diagnosed with at least one of them 250,000 new cases every year and one of the things that is the most distressing to me is the number of children who are being diagnosed with autoimmune disease the average age of diagnosis is going down there are over a hundred autoimmune diseases but ninety seven percent of those that are diagnosed or one of these here the immune system just the definition of autoimmune is when your immune system no longer has the ability to tell the difference between bacteria viruses and your own cells so the body the immune system malfunctions and begin becomes interested in your pancreas or your liver or your thyroid gland or your joints molds Oh autoimmune diseases are very common in fact one of the things I tell people who consult with me is that our first goal is to stabilize you so that the one you have doesn't get worse and maybe we can even reverse it but the most important thing is to make sure that for example if you have Hashimoto's thyroiditis you don't end up being a hypothyroid patient who also has type 1 diabetes if an autoimmune patient lives long enough he or she will almost certainly develop more autoimmune diseases so what are the causes and we're going to talk a little bit about all of these one is genetic susceptibility but it's not as strong as you might think hormones and hormonal fluctuations it's the reason why women develop most out of autoimmune diseases 78% of all diagnoses are in women diet is right up there with the top causes leaky got chronic infections a chronic inflammation asthma and allergies overweight obesity and vaccinations so if we look at genetics you know genetics is the favorite thing to blame diseases on and and the reason I don't like this is first of all the evidence doesn't support it but just as important I think if you think that genes determine your health outcomes that put you in a pretty helpless situation because I don't know about you guys but I didn't get to pick my genes so if you think that it's all about genetics there's really not much you can do about it but if you understand the real causes you'll you'll have a lot more power over what happens to your health future less than ten percent of people who are genetically susceptible to developing autoimmune diseases actually develop them the risk changes over time it changes when people move to different locations there's a lot of there are a lot of migration studies published where you can see the health outcomes from people who live in an area where a particular disease or several diseases the rates very low and then they move to someplace like the United States and within about 15 years now it used to be a generation now about 15 years you see the same incidence of disease once people adopt a Western diet another thing that we see and it's very diet related is that if you do D challenges where you take certain things out of the diet people get better when they start eating them again they get worse and I'll show you some of those before we're finished here now just to give you an idea on the genetics this is a chart that will be hard for you to see but I'll tell you what it says what we have is the few autoimmune diseases and we have the population frequency and then the sibling risk all right so but if you look at this most of them the sibling risk is very low so for example psoriasis is the top one 2.8 percent of the population has it the sibling risk is 17 percent but if you look at also rate of colitis less than ten percent one tenth of one percent of the population has it and only 1.2 percent of siblings get it so it becomes very crystal clear and we even have some studies with identical twins showing that the disease concordance is not very high even in identical twins so a lot of what this is all about is not your genes it's about other things that affect your life so let's talk about hormones androgens or male hormones are more in immunosuppressive than estrogens and we think that that's one of the reasons why females have more autoimmune disease than men testosterone has been shown to suppress antibody production in patients who have lupus for example rheumatoid arthritis patients have low androgen levels so there's a clear hormone connection on the looking at hormones a higher lifetime exposure to estrogen increases the risk so what we see is the earlier age of menarche is an issue women who take supplemental hormones either in the case of birth control pills or oral contraceptives and also a hormone replacement therapy after menopause increase the risk and women who have conditions that are related to abnormal or irregular hormone production so women who have even pms infertility heavy menstrual periods things of that nature PCOS always at a higher risk of autoimmune disease one interesting thing is that changes in hormone status due to things like pregnancy and menopause change the risk so for some diseases when women get pregnant the diseases go into remission and then after delivery they get worse sometimes the diseases get worse one of my most interesting patience was a woman who had managed to keep her ulcerative colitis in remission by having 14 children and and it was a good short-term strategy but this you know menopause happens and we can't keep having babies so now we have to actually address the underlying cause of the disease so that was a pretty creative thing to do I'm not sure I would have been willing to do it you got to give her credit for effort right but but anyway we see that both pregnancy and menopause depending on the disease make the conditions worse or better allergies are a major trigger and by very by the very definition what allergies are abnormal or immune response this is when your immune system starts to misbehave and instead of being interested in bacteria and viruses it's interested in pollen and dust and animal dander and so we take allergies very seriously in my office because we often see that allergies are the first sign of an immune system that's misbehaving and if you don't get those allergies under control and there are a lot of things that you can do in reference to diet and probiotics and things of that nature to calm down allergies and asthma so that this doesn't progress in fact one comment I can make in general about health regardless of what condition somebody has is part of what's wrong with medicine is that it's all about giving you drugs or supplements or procedures or something to kill the symptoms you know so that you don't think you're sick or to deal with biomarkers but the problem is you don't get to the underlying cause which means the person continues to get sick and so that's one of the reasons why by the time people are in their 60s and 70s they're taking so many drugs the original thing that went wrong when they were 42 or 35 or whatever never got fixed so I always liken it I teach through analogy you know if I drive home from the airport on Sunday and the oil light comes on in my car there are a number of ways I can address it and one of them is to pull over to the side of the road pop the hood and disconnect the fuse that lights up the oil lamp and keep driving okay that's called taking drugs that's called taking supplements because we know the end of the story the engines going to blow up my office is full every afternoon with people where the engines blowing up and now we really have to pay attention so I don't want people to be ridiculous about every symptom because you can go the other direction too my elbow hurts do I have bone cancer I've got hangnails does that mean you know something terrible's wrong but I find too many times people ignore the fact that their body is starting to give them clear signs that they're deteriorating and they ignore it and just keep marching along so allergies are a trigger and if you take a look at the and the biomarkers for allergy which include things like inflammatory cells amassed cells antibodies t-cells cytokines these are all the same immune cells that are involved in autoimmune and so it is a natural progression from allergies to autoimmune and frequently when we see autoimmune patients they they have had allergies for a long time sometimes since childhood all right so I'll give you some dietary triggers and and one of them is iodine we are always told and this is another common theme and how diet health and medicine that you need more of everything right and you see this that's where the supplement business has capitalized if a little bit of calcium is good for you then 10 times as much must be fabulous right and if a little bit of protein is good for you well eating 35 times as much as anybody should eat that's got to be better so one of the things that's happened is that people are convinced that they're not taking in enough iodine every day and so they often consume supplements that contain iodine in fact a lot of doctors who I think are not very competent take patients who are showing signs of hypothyroidism and put them on iodine supplements which ultimately blows out their thyroid and we see in areas of the world where iodized salt as introduced one of the first things that happens is within a very short period of time the incidence of hyperthyroidism starts to go up exactly the opposite of what people have been told the average person in the United States takes in about one and a half times the amount of iodine needed daily and then starts taking supplements and drops and all that sort of thing bad idea actually for a variety of reasons another thing is gluten and autoimmune diseases it's a it's a common trigger and it's particularly common with with thyroid disease and I will show you the mechanism of action in just a little bit here I wanted to make something perfectly clear because I'll be talking a little bit about gluten tomorrow there are people who have celiac disease they need to avoid gluten there are people who have something called non-celiac gluten sensitivity and we have a good body of evidence showing that there are some people who have that that is a very small percentage of the population we have a lot of people who've tried to make this into something entirely different where everybody's being told that they're allergic to gluten and shouldn't eat gluten and that's not true one of the things that it has done this craziness is it has made a great market of gluten-free products so that our celiac patients and autoimmune patients actually have something good to eat because the options used to be terrible when I first started 22 years ago but there is a trigger there is a connection and I'll show you quite a few studies that show a connection between gluten and many types of autoimmune disease dairy and animal foods cause chronic and testimony from inflammation and this leads to a condition called leaky gut which we're going to talk about for just a couple seconds and what this does is this allows the entry into the bloodstream of partially digested proteins and and so we'll talk about well how that leads to autoimmune disease but we have animal studies and we have human studies showing that this is one of the main triggers of autoimmune disease so let's talk a little bit about leaky gut and just to tell you what it is so the your your intestines are where nutrients are absorbed and there there's a huge carpet of bacteria called your gut microbiome which is the fashionable thing to talk about these days and that's a good thing actually in fact your microbiome is made up of about a hundred trillion cells bacterial cells that's more than you have in your whole body your whole body's 37 trillion so we're going to talk about this more tomorrow but we're leaky gut comes in is that that Harpeth of bacteria they serve several functions the first thing is they help you to absorb nutrients from food they control your immune system it's the signalling center for your immune system and also they help you absorb nutrients from food so there are a variety of different ways which I'll show you in a minute including eating animal foods that damage that microbiome and what happens is these tight junctions that drag nutrients into the bloodstream become loose and partially digested food fragments start getting into the bloodstream along with bacteria toxins and a lot of other things you don't want circulating through your bloodstream – and what happens is they're targeted by the immune system which is the right thing to do anytime there's something in your bloodstream that doesn't belong there you're counting on your immune system to trigger a response so antibodies are created for what we call these antigens ongoing exposure which is bound to happen if the leaky gut condition continues means more and more antibody is created and so what you end up with is food sensitivities such as gluten dairy that sort of thing the development of autoimmune disease following the development of leaky gut is well known well proven but it's not right after and we were having an interesting discussion from before you and I in the front row before I got up here about the fact that you can injure yourself for a really long time with a bad diet and not know that it's going on in fact I have only one suggestion for an improvement on the human body by design and I think dr. Esselstyn would like this I think it would be great if our the interior of our blood vessels had nerve endings and so what would happen is you would eat like really high fat meals and you'd be an excruciating pain like you'd be on the floor and the fetal position in your kitchen you would not do it again alright so the fact that you can enter your blood vessels literally for years and years and not know of anything going on or feel anything going on until one day you have a stroke or heart attack that's why you have to look at this from an intellectual standpoint and you can't afford to say well I've been eating this way for a long time and nothing's wrong with me so it must be okay well it's okay right now but it may not be okay next week if you have a heart attack or a stroke right okay so what causes leaky gut well meat and dairy does drinking too much alcohol does and unfortunately we still have health professionals who are promoting alcohol is having health benefits it doesn't have health benefits it's at best a tree now if you have like me if you have six glasses of wine a year I don't think you're going to do a lot of damn to yourself but I have people in my office who have three glasses of wine every night and you're doing a lot of damage to yourself alright so alcohol is a treat it's the way at the top of our food pyramid it's not for daily consumption antibiotics are a big one one broad-spectrum antibiotic can wipe out your gut microbiome in just 1012 days all right and we prescribed way too many antibiotics in this country now we know doctors tend to over prescribe but we have to take a little bit of responsibility as patients because a lot of the doctors I talk to say listen I know I shouldn't prescribe so many but patients get mad when I won't give them to them all right so we have to educate people not to ask for them but what happens when you take antibiotics is they wipe out the bacteria that might kill you or you might be able to recover without the use of antibiotics in many cases that's a different discussion for a different day but they wipe out your beneficial bacteria and they cause the pathogenic bacteria to flourish and we'll talk about that more tomorrow cow's milk intolerance and you notice how many studies I have I have probably 2000 studies archived on my server about diet and autoimmune disease again I'm condensing condensing condensing down we could have 25 slides to Stein cow's milk and autoimmune in fact cow's milk is just kind of bad for anything that you don't want to get and somebody asked me I gave a lecture the other night and about about diet and health and and she said is there anything that that that cow's milk is good for I said you know it's really good for growing breast cancer if you want to grow yourself some breast cancer you want to get some cow's milk products and eat them every day because that's one of the quickest ways you can get there patients with inflammatory arthritis more right more likely to have intestinal inflammation and leaky gut so we've looked at some of the causes elevated levels of antibodies to gut bacteria into food have been found in people with inflammatory arthritis and so this is one of the things that happens as part of this abnormal immune response the way that and not just a preview of tomorrow your body and your immune system that should know the difference between you and not you your pancreas versus viruses and bacteria also your immune system is intelligent enough to know that the bacteria in your gut are not you but they're supposed to be there so what happens with autoimmune is those inflammation levels get higher and higher as a result of doing some of the wrong things that we've talked about the gut bacteria start being targeted to remember they are the signaling system for your immune system this is real bad for business so let's talk about molecular mimicry and what this is is the amino acid chain of one protein closely resembles the amino acid chain of another protein they don't have to be identical they just have to resemble each other closely so the way that your body works is you produce antibodies for any antigen foreign thing that gets into your bloodstream and if the amino acid chains that make up those partially digested food fragments look like the amino acid chains that make up tissues of the body we call that molecular mimicry and that can be the beginning of your immune system starting to attack your own body so let's look at cow's milk proteins they're very similar to the amino acid chains that make up the collagen and human joints and so as your as you get a leaky gut from eating poorly or taking antibiotics however it happens drinking alcohol now you've got partially digested food proteins getting into the bloodstream sometimes cow's milk if you consume those cow's milk proteins antibodies are created for those and then those amino acid chains on the cow's milk protein look like collagen and the joints now you've got the beginning of rheumatoid arthritis the same thing is true with gluten proteins and the tissues of the thyroid that type of reactivity so let's talk about type 1 diabetes these cow's milk proteins not only look like the the amino acid chains not only look like the collagen and the joints but they look like the beta cells the amino acid chains that make up the beta cells that produce insulin in the body so here's a typical thing that can happen to a child who drinks cow's milk cows milk proteins or cow's milk was never intended for humans some kids don't digest cow's milk very well in fact most people don't digest cow's milk very well but little kids in particular that's why they should have formula so what one of the common responses to this as kids got infections ear infections ear infections and tubes in the ears are sort of like a passage of childhood I mean it's just like so normal I hear friends talking about it all the time it's like oh you know my granddaughter had the the tubes put in her ears last Thursday like everybody does it right well everybody shouldn't be doing it is my point so anyway what happens these kids get ear infections they take antibiotics that leads to a leaky gut now cow's milk proteins are getting into the bloodstream the body starts to create antibodies to those cow's milk proteins and then goes after the beta cells of the pancreas so how do we know that well in 1992 a study was done blood samples were taken from 142 type 1 diabetes diabetic children and compared to controls 100% of the kids who were diabetic had antibodies to cow's milk protein in their bloodstream none of the controls did so that's a pretty good sign and it's been confirmed by other studies in fact I've I think I've read all of the studies on this topic and I can only find one that did not show this result and by the way just so you know there are no issues we're all studies 100% point in the same direction which is why things can get so confusing which is why it's important to have an evidence filter so that you start sorting out like the preponderance of the evidence and that sort of thing so that's one thing genetically susceptible children who are weaned early fed cow's milk formulas and have leaky guts are more likely to develop juvenile diabetes and one us studies showed that children of this profile who consume cow's milk have eleven point three times greater risk of developing juvenile diabetes that's actually higher than the risk that a smoker will develop lung cancer if it gives you an idea now we don't always know who the genetically susceptible children are so we're just feeding cow's milk to infants and waiting to see what happens which I don't think is such a great idea I think if parents saw this type of information it would cool the enthusiasm for formula I've gotten kind of not so nice about that anymore I had a had somebody the other day tell me that breastfeeding is inconvenient I said well I think if you were looking for convenience this having children thing bad idea there's nothing convenient about having children alright you've got 18 plus years of inconvenience coming up if you do this right the breastfeeding is such a tiny tiny part of this right so anyway this is what informed decision-making looks like a lot of people get angry with women because they don't breastfeed but nobody's showing women the outcomes that happen as a result of not breastfeeding so anyway the risk factors for type 1 diabetes are early exposure to cow's milk proteins in formula short duration or no breastfeeding antibiotic treatment high birth rate weight and rapid weight gain obesity and weight gain even in infants is a risk factor so let's talk about inflammation chronic inflammation can come from a number of places particularly diet and being overweight or obese Allergy Asthma infections and so what happens when you're in a chronic state of inflammation is the immune system is switched on and in some people this eventually switches on an autoimmune response so you can be genetically predisposed and not do the things that we're talking about and not get an autoimmune disease that's me every single female in my family on my mother's side had rheumatoid arthritis by the age of 50 I'm 61 and I don't have it my sister does and she's four years younger than I am so I'm an overachiever and I know that if I wanted to eat my way into rheumatory arthritis I could do it all I have to do is start eating like my sister and my mother and my grandma I could very quickly put myself in that situation probably by Christmas of next year but I'm choosing not to do it on the other hand you can have no genetic susceptibility and if you have enough of this type of thing going on you can end up with autoimmune disease and another thing I'll say about about inflammation and diet just for a second is that a rocket onic isit is concentrated in animal foods and it's a precursor to inflammatory hormones called prostaglandin series two prostaglandins and so people who eat a high animal foods diet almost end up in a chronic state of inflammation just every time they eat a meal it's it's an argument for really reducing our eliminating animal food all right couple of other causes the hygiene hypothesis you know I think it's great that we're a lot more clean than we used to be I mean we used to have sewage running down the street bad idea I get that but but we are trying to prevent anybody from having a childhood illness we're trying to use antibacterial soap on our skin I took a 3-hour CME course one one evening on the microbiome of the skin and how dangerous it is to wipe it out by using antibacterial soap all the time all right so so we we really live in a very clean environment to clean actually and then another issue is antibiotics related to this this raises serious questions regarding our current overuse of antibiotics as well as ultra hygienic environments that many of us live in if the bacteria within us are specific to us and necessary for normal immune system function then it's important to know if we're in fact losing those vital bacteria so and we are by the way Martin Blaser wrote a great book called missing microbes he's studied the microbe microbiome a lot his wife is also engaged in the same type of research and she went to Venezuela and found a population of people who have very little interaction with the outside world and they took fecal samples from these people and found 300 bacteria that are missing from the human microbiome in places like the United States we don't know what that means yet but I can't believe it's really a good idea for this to happen right we'll bring up a controversial topic I'm told I'm controversial and I've thought about that a lot you know really basically what I do is tell the truth and I want to know when did telling the truth become controversial I'm not sure I understand that but in any case I'm not afraid of controversy because I can back up what I say with evidence but the most common autoimmune diseases reported post vaccination or lupus rheumatoid arthritis inflammatory myopathies multiple sclerosis Keon beret and vasculitis and just to give you an idea there's a long track record of this in 1976 the national influenza immunization program began within started a million vaccinations a week went up to four million a week within two months more than ten states have reported youngberry outbreaks and vaccinated people so back in the days when we were a little more responsible about it in December of 1976 this program came to a quick end by January of 1977 more than 500 cases of GBS that were reported some patients recovered completely some partially 25 of them died so the program determined that the risk of acquiring GBS within six weeks of vaccinations was ten times higher than the population that did not have the vaccine so of course the definition of insanity is you do the same thing again and again and hope for different results so we tried it again in 1992 93 and 94 and we had exactly the same thing and now we mandate that healthcare workers get vaccinations as a condition of working in a hospital or medical institution because that makes a lot of sense based on what I'm telling you right mass inoculation was instituted in the US for the swine flu 45 million Americans were vaccinated that was back in 2009 the estimated risk of GBS prior to vaccines one in a hundred thousand the incidence was seven point six times higher within five weeks vaccine adverse events reporting system acknowledge the risk was higher and there's this huge condition echt by the way if you actually read the the drug company's data the FDA website the CDC website they tell you all about this but it gets totally sanitized from the public information about vaccinations links have been established between the DPT vaccine and autoimmune measles and multiple sclerosis MMR and hepatitis B and rheumatoid arthritis and Gardasil and GBS Gardasil is one the most interesting ones right now there's a lawsuit a colleague of mine by the name of Peter Goethe the co-founder of Cochrane Collaboration has filed a lawsuit against the European Medicines Agency for fraud scientific misconduct and fraud pertaining to the Gardasil vaccine Japan has taken it off of the schedule and has open 31 centers to help the injured women and girls from this vaccine so other countries are starting to get a little aggressive at least with that one in terms of addressing the situation I could put up eye about four or five hours of lectures just on the vaccine autoimmune connection but these studies I think are important I'm just going to read you the results of one systemic autoimmunity appears to be the inevitable consequence of over stimulating the hosts immune system by repeated immunization with antigen to the levels that surpass the system self-organized criticality and what that means is that anything that perturbs the immune system abnormally can eventually result in the immune system being switched on and it's unable to switch itself off so just to kind of bring us up to date just to tie all this together think about it taking antibiotics wipes out your gut bacteria now things couldn't get into the bloodstream that shouldn't get in you can end up having allergies as a result asthma as a result you can have autoimmune disease as a result because your body keeps pumping out antibodies that destruction really damages the signaling system and so what happens is the immune system ends up switched on constant antibody is going through the system the way I explain it again through analogies it's like street gangs wandering around in downtown Melville looking for mischief your antibody is looking for stuff to do when they find it they started talking tissues of the body so a similar thing that you could do is if you went home tonight and you flip there's the furnace on and off a nominal if and on and off and on if you did that for four or five hours you just might switch the thing on and you can't switch it off anymore and the next thing you know your house is 140 degrees that's sort of what people are doing with their immune systems in this way so there are problems with confirming associations one of the reasons is vaccine dogma I mean you just have a public health approach to this that says it's the sacred cow you can't touch it we we offer a 25 for 30 hour course just in looking at the science on these issues because the medical journals actually do provide a great deal of evidence that what we're doing is a bad idea but certainly the reason I'm telling you about it is that I see a lot of autoimmune patients change their diet days watch forks over knives something of that nature and they changed their diet they definitely get better but they don't get better enough and one of the reasons is they're still showing up every year for their flu vaccine and so every time you're perturbing that in the in system so it's really important to look at this as a cohesive picture enough and again I'm going to show you a ton of studies with diet but if you take care of the diet and the woman is still having irregular menstrual periods are taking HRT for menopause and having a flu vaccine you're really not going to get very far you have to take care of all of these causes that I'm talking about here all right so the typical approach to autoimmune is to treatment with drugs well my gosh it's the typical approach to everything right we have a drug for that we have a drug for things that aren't even diseases like I love those commercials that the the questions they ask people do you feel shy at a party when there's 500 people you don't know the answer's no to that question right okay so anyways steroids are one of the the biggest class of drugs that are prescribed and they're immunosuppressant but they're not limited to suppressing the immune system as it pertains to the specific autoimmune response for example for just rheumatoid arthritis they suppress the immune system period and for a very long time we thought in medicine that the problem with steroids was if you took them for too long so everybody would try to give small doses short periods of time we actually now have a lot of evidence and I've written a couple of articles on this showing that the first pill that goes in the mouth you have problems some of the side effects of steroids are glaucoma fluid retention increased blood pressure mood swings weight gain clouding of the lens in one or both eyes cataracts high blood sugar which can trigger or worsened diabetes increased risk of infections thinning bones suppressed adrenal gland hormone production thin skin easy bruising and slower wound healing inhaled corticosteroids and topical steroids equally dangerous and the worst thing you can do is inject steroids into a joint which is very common practice to relieve pain because it almost if you do it even once you can increase your risk of having to have the joint replaced later on I think this is an interesting study here one dangerous paradox and author arthritis treatment is that drugs most commonly used to treat arthritis or toxins to the intestinal barrier all commonly used non-steroidal anti-inflammatory drugs and says apart from aspirin and elephant are associated with increased intestinal permeability and Men and so the the drugs that are often given to people to reduce their pain and discomfort increase the likelihood that another autoimmune disease will develop or that the one that people have will get worse because they damage the intestines in fact there's a lot of evidence I don't teach a class in our school or to patients or give a lecture talking about anything where I don't end up talking about the side effects of NSAIDs and how it in how they increase the risk I think personally the drugs never should have been approved and they should not be available without prescription they certainly should not be taken every day which is how they're advertised on TV very bad idea well there are many causes of autoimmune disease diet is right up there so let's take a look at and and this may be hard for you to see this is we call this the informed food pyramid and just real quickly I'll start at the bottom 64 ounces of water and that what did we lose okay well anyway 64 ounces of water and that that is regardless of whether or not you eat a plant-based diet and the reason is you it's pretty easy to take in a couple cups of water from food but a human loses 10 cups of water a day alright through perspiration feces urine sweating and sweating doesn't mean that you have to be like at the gym working out I mean I'm sweating right now talking and so are all of you it's imperceptible but but but you do sweat and that eight ounces has to or that eight difference those eight glasses have to come from somewhere we have some really good studies showing that dehydration increases the risk of a lot of diseases including heart attacks and stroke because the blood becomes more viscous then you'll see starchy foods come next potatoes squash is whole grains legumes root vegetables those those kinds of foods next you'll see steamed vegetables raw vegetables any any way you want any vegetables and then fruit and then you'll see cereals and breads and you know moderately processed foods low process to moderately processed foods I don't think we're probably going to get people to stop eating all processed foods it's very difficult we don't want to make this harder than it needs to I've heard some of the Q&A during the last lecture and people were asking about nuts here's our rule with nuts and avocados and things of this nature provided you don't have serious coronary artery disease I think it's okay to have some of this stuff but the best way to do this because I've learned from 22 years in this business people don't really do well with less more moderate I mean does anybody know what less is more is in fact there's some I read three research studies that looked at this what does moderation mean and you know what they determine that based on the responses they got from people the definition of moderation is how much of something I really like I want to eat right now okay well you know I'm gonna get very far if that's how you're choosing your foods right because I'll tell you what the most dangerous I'm standing over here because the ice creams over there alright so it's very tempting to just walk off the stage and get some right so so the point is we try to stay away from that kind of language which is not very prescriptive and instead we recommend that people eat nuts or avocados when they're in a dish or part of a recipe so I'll give you a couple of examples if I go to a restaurant for example an order of black bean wrap and it has some avocado in it okay what I don't do is buy avocados at the store and bring them home and look for things to eat them with all right avocado toast that let me just put this in perspective one cup of avocado is 21 grams of fat okay so I could be twice this size if I ate a lot of this stuff and it's not about counting calories it's about having some concept of calorie density and and the and how fat promoting some of these high-fat foods are if I make a vegan macaroni and cheese dish and it takes a quarter cup of cashews and it's for eight servings that's okay taking home the bag of cashews insert hand in bag not so good alright so so we allow people to have these foods but we give them some really prescriptive information about how to do it and I think that's the way diet should be taught by the way I've written quite a bit about this and we own the term prescriptive communication as it pertains to diet and what I mean by this is when you go to the pharmacy to pick up a prescription you don't get something and read the label it says hey some pills not too many right it says take one three times a day with food and then people are really diligent about doing I think you have to have the same type of prescriptive communication it's one of the things I appreciate about dr. Esselstyn he's very specific with his patients there's no wiggle room there and they know exactly what to do and that's why some of them live that's why all they all live if their compliance all right so above the above the nuts and avocados and seeds we have and notice there's no oil out to the side oil and let me tell you the problem with oil this is it 120 calories per tablespoon and 14 grams of fat per tablespoon all right so let me put that in perspective okay if I were to add an oil-based salad dressing to one of my salads a day all right that's all I did didn't change anything else and I don't know what else I'm gonna change I eat a pretty perfect diet I exercise almost every day I would weigh 37 pounds next year this day 37 pounds that's a lot all right so no oils and then you'll see animal foods what's that well I'll come to that that's barley rye oats and wheat it addresses the gluten issue so I'll get to that in a minute and then you'll see animal foods are optional two or three times a week no dairy wild Kadir organic we don't take it off the table for most people but we have to limit that more prescriptive communication and you'll see at the top treats and treats are for special occasions so again I don't see I don't think we're gonna get people who are 40 years old to promise they're never going to eat another cookie they'll never have a piece of cake one of the most cognitive common cognitive distortions for people who have trouble with eating patterns and drinking and drugs a lot I think is perfectionistic thinking all right it's one of leading causes of depression so it's a it's a bad way to approach this for most people so treats are for holidays and birthdays so now people will say well what about national kidney donor week is that a holic no we're not talking we're talking about your birthday and maybe your mom's right Christmas Valentine's Day but the reason I'm busy all the time is because people are treating themselves 14 times a day and sometimes they don't even realize that the the foods that they're eating or treats so that's the basic plan and then we'll talk about some of the specifics in the and the research I mean we have we could spend two or three hours just talking about that and I'm sure you guys will have some questions about it now as we start looking into research on autoimmune diseases are really most diseases one of the unfortunate things is we don't have a dr. Esselstyn of the autoimmune disease business I'm hoping sometime we get that kind of data but it's really when you put dr. esselstyn's data in front of the patient as coronary artery disease somebody's had a heart attack it's incredibly convincing everybody agree and and it's so easy for them to see we have to do a lot more digging and connect the dots now it's there in the research and the medical research so I'm going to share some of that with you the biggest limitation in terms of research is that there's so much reductionism in research as it pertains to diet so you deal with a lot of self-reported data from patients and let's eliminate this food one food what's the dietary pattern that makes the difference it isn't and and it's unfortunate because the way that this is all talked about and communicated to patients is they read an article that says blueberries reduce your risk of cancer right and everybody eats blueberries every day at the end of six weeks they get tired of blueberries their health hasn't changed because there aren't enough blueberries on the planet to overcome the dietary indiscretions that a lot of people practice on a daily basis right so so it's the totality of the diet but you just don't see those kinds of studies so back to inflammation and diet the choice of healthy sources of carbohydrate fat and protein along with regular physical activity and avoidance of smoking is critical to fight the war against chronic disease Western dietary patterns warm up inflammation while prudent dietary patterns cool it down animal foods increase inflammation and vegetarians and near vegetarians have lower blood levels of arachidonic acid which is a precursor to inflammation so eating a more plant centered diet now I would love to have a dr. Esselstyn type study to show you I don't what I can do is just overwhelm you with the number of studies that lead to our conclusions here a raw vegan diet including lactobacilli rich and chlorophyll rich drinks resulted in improvement of symptoms for rheumatoid arthritis pain an elimination diet reduced ra symptoms lower fat diets reduce the onset of autoimmune disease an experimental vite my so from you see this all the time raw vegan diet for a period of time lowering the fat but you start to get a clearer picture if you put all these things together not necessarily the raw vegan diet because I don't think that's real sustainable over a long period of time but but the low fat higher fiber more plants less animal in this study 24 out of 72 rheumatoid arthritis patients improved on an exclusion diet so you might say well that's not very many well there remember this is an exclusion diet where patients are self reporting but look at what they were reporting 14 patients responded to grains as a trigger milk for people nuts eight people beef four people cheese seven people eggs five people one each to chicken fish potato and liver now the study would have been entirely different if they put all those people on a starch-based plant-based diet for a while you would see a different result that's what we see in our office every day 71 patients with rheumatoid arthritis showed improvement after two weeks when pulses cereals milk and non vegetarian protein foods were illuminating very low fat diet resulted in complete remission and six patients with rheumatoid arthritis symptoms returned within 24 to 72 hours after eating a high-fat meal a high-fat meal with foods like chicken cheese soft flour oil or coconut oil in other words you can make progress and undo it with one animal foods based meal all right if particularly if it contains high fat and dairy the authors concluded dietary fats and amounts normally eaten in the American diet caused the inflammatory joint changes seen in rheumatoid arthritis forty six adults with rheumatoid arthritis eliminated dairy products and cereals thirty six or seventy eight percent responded seventeen clearly improved nineteen were in complete remission for one to five years eight of those were able to stop all medications now to put that into perspective with autoimmune disease drugs can give you very short period of time five years is sometimes a miracle diet alone is capable of producing that gluten intake is linked to Hashimoto's and Graves disease celiac disease rheumatoid arthritis inflammatory bowel disease and leaky gut autoimmune patients should eliminate high gluten foods and that's barley rye oats and wheat so that's where the brow comes from that you're asking about earlier now some people say well oats don't contain gluten and you're right about that but a study that was done in Canada that sampled oats from all over North America concluded that 88% of the oat supply in North America is contaminated with enough gluten to cause a response in a celiac patient so that's why we tell people to eat gluten-free oats and and we err on the side of caution because the people who come to us are pretty sick so we think it's more important to err on the side of cautions and it's pretty easy to get gluten-free oats almost anywhere so those are the four foods they can eat any other grain that they want and we distinguish between the person who has autoimmune disease and celiac which is an autoimmune disease but the celiac patient the intolerance to gluten is so much that just a tiny drop of it and soy sauce is enough to flatten out the villi and cause the disease to progress this is not the people who have autoimmune disease they don't have to eat what we call a medically gluten-free diet a study of patients with rheumatoid arthritis patients improved when diets were improved conditions worsened when the patients reverted back to their normal diet research has stated that the improvement was due to the reduced intake of potential trigger foods we do scut permeability weight-loss and lower production of inflammatory hormones 7 out of 15 patients with rheumatoid arthritis went in to remove a mission when dairy was eliminated a study looking at the relationship between cow's milk egg proteins soy milk and arthritis and experimental animals showed that there was no reactivity to the soy milk a lot of reactivity to the cow's milk the eggs so again animal food cow's milk in a six week placebo controlled single blinded study of 48 patients 48 patient 48 of them were able to identify foods that cause symptoms cereal foods such as corn and wheat produce symptoms in more than half a follow-up study of a hundred patients who had used dietary therapy during the previous 10 years showed that one-third were still taking no medication alone on an on diet alone the most common foods causing reactions cereals and dairy so again you have to connect the dots here but I have probably as I mentioned I've got a couple thousand studies archived on my server and after you see study after study after study after study where the patients are saying when I stopped eating dairy I get better when I stop eating high gluten foods I get better that becomes difficult to ignore and the absence of a long term longitudinal study I don't think can stop us from our should stop us from acting on this high intake of dietary fat damages the intestines and that's what I was talking about earlier a vegan diet changes the fecal microbiota bio flora and rheumatoid arthritis patients and that's why we have to have autoimmune patients take probiotics if they're going to get better they will get better on diet alone but they will not get all the way better most of the time if they don't restrict certain foods eat a low-fat diet take probiotics avoid vaccinations and a sign get their hormones under control if that's an issue fiber and this is we'll talk about this more tomorrow but your beneficial bacteria love fiber and if you eat enough fiber your beneficial bacteria will create produce all kinds of anti inflammatory chemicals that help to keep your body in a low state of inflammation instead of a high state inflammation and also to protect the microbial environment in the intestine here are some studies on leaky gut and improve eye otics-rio a key got now we have a lot of studies that show that we have hundreds of them that show that one of the reasons by the way if you're frustrated with doctors who don't know a lot about this one of the reasons doctors don't know a lot about this is because most of the studies regarding probiotics have but were published after 2004 well my gosh I was out of school by then I was like the oldest person that ever went to naturopathic medical school I graduated at 44 but but most of us we were when we were in school we just didn't there wasn't much of this research to look at so it has contributed to problems with patients getting the right type of therapy then we have some specific studies I can show you 45 adult men and women with symptoms of rheumatoid arthritis were randomly assigned to take probiotics or placebo once a day for 60 days in addition to their medications there was greater improvement and the patients who took the probiotic so you're not only healing up the gut with the probiotic but you see a marked difference in inflammation levels joint pain stiffness and that sort of thing within a few weeks that's starting to take the probiotics sometimes we end up doing an elimination diet knowledge I think this is probably one of the most interesting things that I've noticed or worked on in the last several years so we have people we do a complete whole person approach to this where people restrict the brow foods and no dairy and low fat and eat a plant-based diet and don't get vaccinated all that kind of stuff and in most in all cases people get better but sometimes you have people that will say I know something's clearly wrong because on some days it's a little worse than others so we do an elimination diet where we restrict their intake to just a handful of foods and then after if they become asymptomatic on that very limited diet we know it's a food trigger and then we start having them introduce one food at a time and what we found which is very interesting is that people talk about nightshades being bad for autoimmune patients it's usually not nightshades and even when it is it's not all of them and so I had one person who when she eats bananas it triggers her psoriasis to flare up again now who would have thought bananas another one of my folks corn did it no other food so the bottom line is that it's highly unpredictable it's led to a lot of identifying triggers that we probably would not have paid much attention to I never would have thought to tell a psoriasis patient to reduce their intake or avoid bananas we wouldn't have found that out any other way so that's what we can do if we still have symptoms that we need to get rid of one thing that is an issue with autoimmune patients is that a lot of times they have comorbidities due to the drugs that they've taken the other conditions they've developed and so we have to work on those things – loss of bone mineral density is real common which can be resolved with sunshine making sure the GI tract is repaired exercise builds bones you know bone is living tissue you got a new skeleton every year but you got to stimulate that with movement and we do have a very sedentary population I mean I don't know I remember every time we talk about sedentary people I remember that episode of friends when Joey and Chandler got those black chairs does anybody remember and they sat in those chairs with the remotes and their phones and they did not get up they even had their pizzas delivered across the hall and brought over so they wouldn't have to get up out of the chair right well we're not too far from that right now I mean I have people that avoid movement at all cost and I used to do that I used to put my garbage cans on the car and drive him to the street so I wouldn't have to move right well nobody told me not moving was a bad idea for the first 20 years of my adult life but it's a very bad idea so anyway you can rebuild your bones if you're willing to do exercise flare-ups are usually a result of non-compliance on the diet or stress but what happens is the floor ups which almost everybody has they become less common more space between them less severe until one day somebody wakes up and says I can't remember the last time I had an episode and then we know that we've really put the disease in remission one thing that we do too with people I don't know how many of you know about True North and California they probably are going to name a building after me I've sent a few hundred people out there because I love those people they do a great job and water only fasting has been shown to be effective and just so you know the studies and I'm going to show you here and I won't read them to you it's just that people get better when they fast and then and then they get worse when food is reintroduced and it's not because you can't eat and have to fast for the rest of your life it's because these studies show that people stop eating anything and fast guess what they do when they start eating again they go back to eating dairy and high gluten foods and too much animal food and you know so going out to true north and fasting and then going back home and ordering a steak not going to help you a whole lot right so you see but but the point I was starting to make is that none of these studies I'm showing you here we're done by the people who own TrueNorth all right so this is this is all done by by other people so what we'll do many times for people who have had autoimmune disease for a long long time is will get ammonia health-promoting diet which is I think better if you send somebody to fast after that and then send them out to true north and you see time after time as these studies show that people get better and so that's become a staple recommendation for people who are in a position to do it and it's actually not that expensive their rates are very very low less than the deductible if you're going to be on drugs and have procedures for the rest of your life because you have autoimmune disease one thing that this study points out that I think is interesting is just fasting improves the permeability of the gut now it doesn't mean you don't take probiotics and dr. gold hammer at TrueNorth recommends them but but just fasting starts to allow the gut to heal one reason you're lowering the inflammation levels from eating all the bad stuff that's you're eating that got you there in the first place and then this is a this is a typical example of patients who I think I'm let me see if I was patients who improved when they're fasting and then they get worse when they start eating again so we see that all the time and I won't read these to you but but there is quite a bit of evidence out there one after it says see how many there are right and for rah doing all kinds of autoimmune diseases we're talking about rheumatoid arthritis etc so by the way the one that you can't reverse is type 1 diabetes whether you fast or whether you don't all right so the best thing to do is is water only fasting followed by a program of dietary excellence that that like the one that we've been talking about now one thing I'll mention is I think that fasting should be done in a supervised environment because somebody should be checking every day so I tell people don't try to fast for two weeks at home on your own I don't think it's a very good idea particularly if people are taking medications they may have to come off of medications before they can fast or the fasting itself may make the medication withdrawal have to happen so that should be done with some supervision so I'm a fan and if you've never been out there it's it's a wonderful place they do your laundry you have cable TV they have lectures you forget that you're not eating even though they're preparing food for the people that are being refat and the people who aren't fasting and it really doesn't bother you after a while and most wonderful medical care I think I wish we had one in every single city I think it would be terrific ok so I just want to spend a little bit of time at the end here and then we'll take questions on multiple sclerosis which is a little bit of a different animal but we have a little bit more research on the diet angle here multiple sclerosis about 400,000 people in the United States have it it's usually diagnosed between the ages of 20 and 40 women are three times more likely to develop it than men again we every autoimmune disease we see based almost every autoimmune disease we see basically the same thing there are two types relapsing remitting and primary progressive relapsing remitting means that you have an episode followed by a period of remission and one of the things about this is that I think drugs get credit for a lot of what would have been spontaneous remissions for a period of time before the disease starts to progress again so I think that makes the medical literature kind of confusing on the efficacy of drugs although I'll show you some pretty good data on the efficacy of drugs so it doesn't really matter how it starts in other words if it starts relapsing remitting it doesn't mean that you're not going to be miserable at some point in time at some point in time almost every autoimmune disease including MS starts to progress so what are the causes well you know again we have people who say we don't know we have people that say it's genetics studies show that in areas of the world in which saturated fat consumption is higher the incidence of MS is higher – like the United States Canada and Europe this relationship is even true with in countries like in Norway the diet is much lower fat at the coastal areas than it is internally and you see a difference in the incidence of multiple sclerosis there cow's milk was found to be as predictive for cow's milk consumption for the development of MS as living in a northern altitude and there is some element of molecular mimicry which I talked to you about earlier so doctor Roy Swank was the grandfather of research on multiple sclerosis he this is his theory and he proved it with a great deal of research that sometimes ms begins in infancy formula-fed babies lie down lay down a very poor foundation in the myelin that becomes more susceptible to injury later a virus or a bad diet lots of different things can happen that injury the nervous system and these injuries are almost always near blood vessels which cause Smike to believe that a diet that caused injury to the blood vessels might be a contributing factor to a neurological disease according to several papers that swank authored and he authored quite a few when people eat a diet high in saturated fat the blood cells are coated and stick together the GAM then clumps form in every capillary oxygen tension in the blood vessels drops this disturbs the blood-brain barrier allowing substances access to the nervous system that would not normally cross the barrier antibodies to food proteins resulting from leaky gut attack the milan swine concluded that ms was a result of the weakening of both the blood-brain barrier and the intestinal mucosa in other words he was talking about leaky gut a few decades before everybody else started talking about it so here's one of his initial group of people he took a 144 patients from the Montreal Neurological Institute and they followed him for 34 years he was sort of the dr. Esselstyn of multiple sclerosis the patients were placed on a low saturated fat diet 1 to 15 grams a day the progression of MS was stopped or reduced or stopped reduced or stopped by the low saturated fat diet the reduction in fat was effective even for those with advanced MS at the start of the study the first year there was a 70% reduction in what's called exacerbations flares of the nervous system disorder 5% per year after that 95% total reduction at remain constant for 16 years and he reported that only 1 in 500 patients did not respond to dietary intervention so we can say to omit multiple sclerosis patient with a great deal of certainty that you are likely to benefit from changing your diet highly likely to benefit from changing your diet so here was the summary of what he found 95% of patients consuming a low saturated fat diet remained normal or only mildly disabled at the end of 30 years and only 5% died 80% of the patients who continued to consume the high fat diet died 80% versus 5% that's a huge difference he published a lot of additional study studies documenting his success with over 5,000 patients and other researchers have confirmed his work now I mentioned this before the drugs are incredibly ineffective for MS and I think they get credit for the relapsing remitting pattern in the beginning for example interfere to interferon beta which is a common drug and by the way why do I show you this because this is part of informed medical decision-making if you're having trouble getting patients to change their diet to a plant-based diet show them what happens if they just take drugs so among patients with relapsing remitting ms administration of interferon beta was not associated with a reduction and progression of disability the ultimate goal of treatment for ms is to prevent or delay long term disability our findings bring into question the routine use of interferon beta drugs to achieve this goal in ms so I'm going to show you something that it would be funny if it weren't so serious alright so the multiple score is this risk sharing scheme was developed by the National Health Service in the UK in 2002 and what happened was that there was an interesting observation made which was that patients who had no treatment who had multiple sclerosis were doing better than the patients with treatment so the NHS managed to extract a promise from the drug companies that what they would do from now on is they would pay the drug companies based on how effective the drugs were does that sound fair I think that's fair alright so that's what what the what the plan was so this went on for a little while and patients basically taking the drugs were worse off than the patients who didn't take the drugs and so the NHS said to the drug companies will you owe us money because now we have all these people that have been harmed by your drugs and it would have been better if we did nothing so you're gonna have to pay well if the drug companies refused to do it and you could follow the story in the British Medical Journal for a good long time while they've fought over what to do and it never really did get resolved but this was the conclusion and I think this is important to read outcome based scheme should probably be avoided if all possible if at all possible in other words if you're going to come up with this pesky evidence stuff that shows that what we're doing is a bad idea maybe we just shouldn't look are you kidding me okay but this is what happens when you start looking at the evidence in fact the Cochrane Collaboration which is the most one of the most independent research organizations on the planet said that the use of the best drugs that we have available which cost about fifty six thousand dollars a year for the average IMS patient have absolutely no effect and the same number of people will be disabled wheelchair-bound bed-bound or dead at the at the end of any period of time you want to measure whether they take drugs or take no drugs same thing alright so that's makes a pretty compelling case for diet don't you think and it's surprising when you show this information to people how many MS patients say give me the plants okay I totally understand what you're talking about this is a path to nowhere eating the plants is the path I want to take so the bottom line is that autoimmune diseases are usually a result of poor diet and lifestyle habits which lead to things like highest Regine levels Lika molecular mimicry chronic infections chronic inflammation allergies asthma and if we change those things you can change the outcome and most importantly you can keep more autoimmune diseases from developing I had somebody in my office a couple weeks ago three weeks ago who had seven autoimmune diseases seven of them the original one she had went back to when she was in grade school small patches of psoriasis which people thought no big deal well small patches of psoriasis turned into more psoriasis which turned into rheumatoid arthritis which turned into Hashimoto's thyroiditis which turned into lupus which and it went on and on alright so we're in the process now of trying to fix that I wish I'd had her long time ago all right so that's my story I'd be happy to take some questions about this yes ma'am my favorite part is the QA has been so informative I have I have been seeing a lot of people even as a young age being I guess diagnosed with Crohn's disease that's my practice specialty we're going to talk about and yeah it's not only indices and there are seven years old and they're being prescribed Remicade maybe years yep so I don't know if it's something I should wait on yeah are you gonna be here tomorrow yeah because I'm gonna talk about it I had my eye one that was born with Crohn's disease taken to the hospital with a bloody diaper at seven days old so yeah the age is coming down I'll tell you more about that later but yeah yes ma'am uh you had small intestinal bacterial overgrowth on one of the slides can you make some comments about that it's it's just a another way that gut bacteria end up where it's not supposed to be and beneficial bacteria are wiped out it's really not a separate disease and you treat it the same way that you treat the whole gut problem you have to clean up the diet you got to stop using antibiotics if you can there are a lot of plant antimicrobials that you can use instead of antibiotics and it's advisable to do that and then start eating a good diet and and eventually you can clean up that problem so people have turned it into a separate condition because there's more money in it let's take somebody over here there you go and I'll move back from here okay we'll make sure we get some depth in it is yes ma'am are there times when you have an acute inflammation and you try to do it on your own and it doesn't work and you do take antibiotics but the doctor says you have to take the full course and I've not done that what soon when I start to feel better I wait another day and yeah I figure my immune system will take over the the evidence is clear that you should not take the full dose everybody always said and I've published there I've written articles about this but but the medical journals that several articles saying that and particularly in this day and age see what's happening is that is we're seeing now c-diff and community settings mersa and communities that you don't have to go to a hospital get see deformers anymore so this idea that you take the full course of antibiotics you almost most people don't need to do that so yeah you you're doing the right thing okay let's get somebody right over here no you were looking at yeah you who are turning around we're gonna do you next there you go I was just wondering whether or not you have a similar study on chronic fatigue syndrome Emme the same way you have MS chronic fatigue syndrome is interesting it's often accompanied by irritable bowel which is different from inflammatory bowel which we're going to talk about tomorrow both of those conditions have a very strong psychological component and often the patients will not get better and and I'm going to make some statements and it may bother some of you but I just kind of tell it like it is one of the problems that you have with patients who have chronic fatigue and an irritable bowel but particularly chronic fatigue is secondary gain so people get to the place where it's better for them to be sick in their mind than it is for them to be well which means that they're very resistant to the idea of getting well so there was some discussion when dr. Campbell was up here about psychological connections with illness and it's a big one and in almost every chronic fatigue patient I have worked with what the pattern of behaviors seen or pattern seems to be is extremely high over achieving type of people mostly women who at some point in time have some abrupt they almost know when the line of demarcation is when their health starts to decline and they get to the place where they are completely non-functional now I've seen men like this too and they fall into the same profile they then go to a lot of doctors and and part of the problem is that most of the advice that gets terrible yeah but but even so they don't get better and they don't get any better in my office either unless we deal with what is it that caused you to think that it was easier to be sick than it is to be healthy and so this this isn't a character defect that I want to make this very clear I often in one case I had a young man who was in my office with chronic fatigue and after hearing the story of these overbearing parents who were pushing him to be an athletic superstar when the guy you know wanted to be a plumber or whatever I would have gone to bed and not gotten up to I'm serious I understand where it came from but but you got to fix that because what happens in the mind is that this black-and-white perfectionistic thinking things steps in where I have two choices stay in bed or go back to that well those aren't the only two choices but when you have that type of cognitive distortion you're not going to fix it until somebody helps you resolve it so they're exceptions obviously to the rule and there are some people who change their diets and get better and chronic fatigue patients need to but I've had quite a few vegan and chronic fatigue patients who weren't any better from eating a vegan diet because the mental issue was not resolved okay yes right there yellow yeah when it comes to the probiotics when I take look at the probiotics aisle there's frigerator not refrigerated yeah 50 billion 150 billion you know what how much billions and for well you got you have to work with somebody most most of the people I would say probably 95 percent of the people coming in my office who take a probiotic or either taking something they're usually taking something that can't possibly help them either because it's such low potency they're on track to heal they're got by the year 2080 one or it's got so much stuff in it that they're hurting themselves instead of helping themselves and so it we sell probiotics in our office and the only reason we do I tell people I will give you instructions to go get one or you can get them here the advantage of getting them here is that we have them shipped just in time from the factory that you don't have much degradation if you get them the next day and that sort of thing so that's why we have them but we are very specific about type so you can go buy one on your own you can get them from us but you have to get the right as you said number of billions the right strains and then you have to step it up in other words the product you start with is not going to be the product you end up with so we'll talk about that tomorrow with the GI stuff we'll get into that a lot more the refrigerator not refrigerated doesn't make as much difference as the length of time between when they leave the factory and you put them in your mouth okay a refrigerated product that's been on the shelves for six months is just as bad as one that's it's probably worse than a non refrigerated product that you put that came from the factory four weeks ago okay let's go in the back over there the guy was hand every yeah Thank You dr. popper two questions one I heard you recommend or suggest TrueNorth for someone with type 1 diabetes so for that individual we have a friend that would TrueNorth followed by a whole food plant-based diet how much would that help number one and number two we have another friend who has I believe it's called Mercer's disease which i think is an autoimmune disease how much would they benefit from a whole food plant-based diet and do they need to consider gluten free do you think any autoimmune patient in my opinion should have not gluten-free but restricted and in eliminating those Brau foods all of them ok all autoimmune patients in terms of true north I don't think true north will fast a type one diabetic because it's not safe they can do juice fasting but they have to they have to eat so but having said that accepting the type 1 diabetics most autoimmune patients would benefit from fasting if they had the opportunity to do it having said that also we have many people who get well and never go fast I mean the vast majority of our people do not go fast and they still experience health improvement ok who's next let's do you next I've got you right you're getting your exercise today it would be nice if I just took them in row right yeah well hi hello I have two quick questions I always thought that you had enough probiotics than you got if you add if you ate a very good whole plant-based food diet and the other one I was just shocked I had never heard that you could stop an antibiotic course mid-stream yeah let's start with the with the diet to see the the issue with the microbiome is that these are not part of your body these these critters are renting space from you they're renters alright and so this is like when people say I'm going to eat well and hope to repopulate my gut that's like saying my tenant moved out of the apartment building I'm gonna stand on the sidewalk and hope somebody shows up tomorrow morning living there you got to go get a tenant alright so you have to add a certain level of destruction you have to replace the appendix used to be the backup like when we in the days when we used to get at cholera and you'd have diarrhea uncontrollable diarrhea if you survived you get some repopulation from the appendix but we have an epidemic of appendices appendices being taken out that shouldn't be taken out and the level of antibiotic treatment is so horrific now that even that's being wiped out so you've gotta have to take the probiotics okay and your other question again I'm I'm shocked I've never heard that you yeah well again most most medical practices don't follow the evidence which is why it's so important to make informed decisions and do the research yourself and so what we're trying to do are our endgame and we do it with all of the people who we work with is that informed consent in the healthcare business usually means doctors tell you what to do we call that informing and you say okay and we call that consenting then later on you find out what the medical research shows really should be going on so there's these articles that I've I've been reading for the last 10 years about the fact that it's not important to finish the whole regimen but once something becomes a practice one of the problems we have in medical training is that you have people who practice medicine teaching people who are going to practice medicine now there's some good in that but what also happens is a lot of bad habits get passed down from generation to generation it's really hard to break the cycle and that's why some of this stuff continues okay I'm gonna make it easy on you right next to her there you go I have two questions too if you can okay I'm suppose I'll try to remember the second one right the first one is that my mother she's had a persistent itch in her ear for some time it comes and goes and she's gone to the ENT and to the allergist and they they haven't been able to help her get it better so I'm thinking it might be something in her diet might be that's causing it it might be or it may be that she's got some yeast in her ear that would be causing it that could be something too I mean I I don't know it's hard for me to wait no stuff from the stage right I could I should suggest her to go to try go to a nutritionist I guess well I think you have to go to somebody who who knows something about this stuff I mean the the flavor of the person is not as important as the evidence-based nature of what they do and by the way we were having a discussion earlier about this labeling okay so people say it was what you do naturopathic well I'm a recovering naturopath just so you know I try very hard to leave my training behind so I don't hurt people all right but so so I think a lot of naturopathy is terrible I think a lot of traditional medicine is terrible I think what you have to do to say we don't care what where it comes from we care what the evidence says about the particular thing that we're looking at the same thing is true with the type of practitioner I mean I've met athletic trainers who know more about how to help people recover from musculoskeletal injuries than orthopedic doctors right so so what you're looking for is people who are competent and they're out there I mean we're there you know see you just want to get people who are competent and follow evidence and interview them you know people interview babysitters people interview people who walk their dogs for crying out no interview people who are going to do medical intervention with you so what's your second question to ask you about what's your thoughts about vaccinating children well my I don't have any thoughts about anything this is an evidence based discussion nobody should care what I think about anything okay so let's just look at what the evidence says and this is again a really controversial issue and we're gonna have a very robust talk about this at our full conference in Columbus because I invited Cheryl åkesson to speak who's done a lot she's an investigative reporter has worked on this issue here's the problem with vaccinations the first thing is we know they don't work the flu vaccine efficacy rate is 10% this year the it is now clear there were 150 outbreaks of mumps reported by health departments and so you know what the CDC says we're going to have to give more boosters okay right now whooping cough has been outbreaks in 49 states they estimate that the vaccine lasts for a year I mean if we're going to use vaccines to prevent these diseases eventually we're all going to be walking around with an IV drip bag okay the second thing is that the medical journals are quite clear I wrote a five or six page article on tetanus you know the tetanus infection rate started dropping in 1870 so the vaccine didn't get introduced till 1947 and everybody says that we're preventing tetanus because of the vaccine well that's clearly simply not true and I'm not talking about third-world country medical journals I'm talking about the journal the American Medical Association New England Journal of Medicine etc so these vaccines number one are not responsible for reduction in infectious disease for the most part they don't work for the most part and the doesn't how many people know that there's a court that administers claims for vaccines okay most of the people in the room don't most people who come to see me don't so this is a great plan a few decades ago I think it was 1990 shortly before then the federal government entered into an agreement with the vaccine companies to exempt them from any liability for the damage their products caused and then they charge a tax on the vaccines and it goes into a fund and it's paid out through a court now I'm ninety-nine percent of the people in this country don't know about this court and everybody claims there's no problem but they've paid out 3.4 billion dollars in claims that's a lot of money for a problem we don't we've claimed not to have and also when most people don't know they can file a claim it's the shortest statute of limitations of any courts in the country now I want you I'm going to ask you this how many people would want to buy a car if the federal government entered into an agreement with automobile manufacturers to hold them harmless from any damage their cars do so if the brakes don't work or they spin out of control or whatever or things blow up then we just collect $250 tax per car and put it in a fund and all the people who get hurt driving defective cars can file a claim how many people would buy a car under those circumstances so here's where I am on the issue there's so much fraud and deception when I tell you fraud and deception you have no idea that guy Paul off it they put up there as the poster child he owns a patent on a vaccine with Merck and he he was on the vaccine committee at the CDC that determined the schedule I mean you've just this is criminal activity in my opinion so I think we have to stop this nonsense stop it do the right research and then see if we're going to go forward that's not what are the odds that's going to happen No but that's what I think needs to be done and I'll keep talking about it and maybe we'll start a revolution and actually do it you know yes ma'am right over here I was diagnosed with Hashimoto's about 12 years ago and was told that I have to stay on synthroid for the rest of my life mm-hmm now I'd like to get off I don't know the best way to wean myself off I know a plant-based diet will help but you might stop this you may not be able to get off okay it just depends on what your antibody levels were and what your health status is and so when you start well I think it's very important not to promise things that you can't deliver so when when people start when we start down the path with somebody like you what we're gonna do is we're going we're going to do everything we can first of all to make sure you don't get another autoimmune disease because you're if you if you're not doing all the right things you're prone to get another one then what we'll do is see how far we get with that and if we can reduce that we can try some some reductions in medication but after 12 years I can't say that you would be able to get off medication you might not but if it's a lower dose and you don't get more autoimmune diseases we still win right okay yes you hear you say more about when you said chronic fatigue was psychological and you say the same thing with irritable bowel can you comment on the irritable bowel it's the same thing and you see the same pattern the people who have just irritable bowel usually stay functionalized and they're going to work and that sort of thing but but they and again I'm generalizing there are exceptions to the rule though the people with irritable bowel they're still going to work in school and all that kind of thing but but they're always looking for the bathroom and talking about the limitations on what they can eat and they stay home from work and they're sick and and it's a pattern and just to be honest my mother had this pattern the only way my mother knew how to get attention was to be sick and if you did propose anything that would actually get her well she was highly resistant to that idea okay particularly if it came from me alright so so in case any of you are feeling bad because you haven't been able to convince your family and friends I have not been able to convince my family and friends my father by the way it eats this diet and as 87 years old takes no drugs his IQ is higher than his cholesterol so he listened but the rest of the family not so much the rest of my friends not so much so anyway okay let's write here thank you so much for doing this I just I had asked before about this but I'm someone with lots of allergies and like esophagitis depression what would you say about that he's got like my son he's got oral allergy syndrome so I can eat more stuff and so he's across the board with nuts and soy well we have to figure out what's causing it you have to get to the root cause well and I don't know what the root cause is because I and I can't figure that out from here right I'll say something about depression and I'll talk about in a general sense so just so you know there is no such thing as a chemical imbalance in the brain that causes any psychological disorder no such thing the study that was used for the justified drugging 25 percent of the population was a study that was done on rats who appeared to be depressed I've always wondered how you can tell if a rat is depressed on autopsy they ground up the brain and assayed the material and found out that the depressed rats were low in serotonin now that is by the way the only way we know how much serotonin is in your brain is to grind it up and assay the material which we do not recommend all right never sent anybody for that test ever in 22 years okay so where this came from one of my business partners is dr. Peter Breggin in Ithaca New York the psychiatrist who never has drugged anybody in 50 some years he was he's called the conscience of psychiatry because he started speaking out about this in the beginning and essentially psychiatrists had gotten themselves into a bit of a spot because of some of their terrible practices I mean these are the people that lobotomize one of the Kennedy kids and we're doing electroshock and the in the mental institutions and making deals with prisoners to lobotomize them if they would agree to it they'd go free but they lied about it so they had lost a lot of their reputation and they got the idea that if they could wear white coat some prescribed drugs like real doctors then they could gain their prestige back and the drug companies essentially accommodated them the outcomes on the drugs are far worse there is no chemical imbalance in the brain but if you take the drugs you'll end up with one and that's all of them ranging from ADHD to antipsychotics getting off of them is difficult it's harder to stop taking xanax than it is to stop taking heroin so it has to be done very gradually we got the first course approved through our school called how why and how to withdraw from psychiatric drugs to teach practitioners how to take people off the drugs because the psychiatry profession is pretty hostile to the idea in general but there is no don't let anybody drug you or your kids for psychological issues what most psychological issues are is distorted thinking that has some origin and something that happened to people and many people get in trouble I mean I've had periods of time in my life where I wasn't very happy about a lot of things I didn't need drugs I needed to talk to somebody I need a time in the case of grieving over a death something of that nature so if the answer is not drugging and we're spent we the problem we have right now 25 percent of the people in the country take the drugs it is the leading cause of disability we put a 850 adults and 250 children a day on disability due to these drugs it's a financial behemoth this country can't afford and so um yeah we could talk a lot about that I mean I'll be around for the weekend so we can talk more how do you find out what's causing you have to sit down and talk to somebody who has a clue the whole look how you find it out is you got to sit down how I find out is people submit history people fill out a lot of forms when they come into my office and we have a lot of discussion and we felt by phone if it's not in my office and and we figure out what happened I mean unfortunately right now the 7 minute doctor visits you give me a symptom and I'll give you a drug or you go to the naturopath you give me a symptom and I'll give you a supplement has totally displaced the discussion about what happened to you what happened to you and when did it start and you know something people know a lot about their health and I tell people tell me the beginning of your story and they almost know exactly the beginning of the story a woman will set my we'll be on the phone and she'll say you know I started having a regular menstrual periods in college and then this happened and then this happened and then this happened and then these seven things happened and then you know here we are right today so you have to start looking at what happened to the person and then you can start to figure out how to fix what happened to the person all right so there are no shortcuts I mean you just have to do this work and it takes time and the medical system as we've set it up right now doesn't really allow much time for it which is very unfortunate so just one more thing I think we're out of time for questions but I am gonna come over here sign books I'll talk to you for as long as you want to talk I'll stay around after the panel discussion I put out a newsletter on Monday that has an article about health it's free I put out video clips on Tuesdays and Thursdays free you can sign up when I smile put my signup sheet there feel free to sign up for the free stuff and thank you so much for listening [Applause] you


  1. "If I had known then…" If I had known I was newly pregnant, I would NEVER have gotten a flu shot. Killed my baby. Never again.

  2. Wondering if the cow’s milk issues occur more in the white population – children from South Asia (India, Pakistan esp. Punjab) for example, drink (and have been drinking) plenty (and I mean A LOT) of cow’s milk (fresh, unpasteurized from cows that did not get growth hormones or antibiotics) from generation to generation and we don’t see an epidemic of Type I Diabetes there as we do here in the West. Vast majority of kids in South Asia (with few exceptions in urban areas) are also breastfed as infants – could that be protective to some degree? Also, there are several other gut health offenders (much more aggressive vaccine schedule, being given formula as opposed to breastmilk in infancy, processed food consumption, non-organic diet etc) here in the West than in South Asia. How do we know those other factors are not contributing to the observed high prevalence of Type I Diabetes and adding cow’s milk to the diet of a kid whose gut is already damaged from all the other offenders only complicates the problem (and not ‘create’ it as is being suggested in this talk)?

    The only way we can say CONCLUSIVELY that cow’s milk is a major cause of Type I Diabetes is if we, not only, see the same (statistically significant) association between the two but see it across the globe and NOT just in specific demographics or ethnicities AND that association must continue to be strong even when other possible contributing factors (confounding factors) are removed one at a time as the results are being studied. In the absence of that, I don’t see this as being a GLOBAL problem, just something more endemic in the West and possibly a result of the combination of unnatural farming practices & the shenanigans of Big Pharma & the food industry quite common here in the West.

    Generally speaking, for whatever reasons, I have seen kids born and raised in the West to have much weaker guts with all sorts of digestive issues than those from developing countries so I am sorry I am not drinking this Kool Aid about cow’s milk being the culprit when it can be, and most probably, is something else. And the premise that Cow’s Milk was not designed (by God / Nature) to be consumed by humans is completely false because if it were true then it doesn’t explain why we already have an enzyme in our body sitting there ready to digest it! a NORMAL human gut is pre-equipped with an enzyme (lactase) specifically designed to break down milk (both human and cows … or even goats and milk from other milk producing animals) – So when a minority of the human population lacks that enzyme we are talking more about an ABnormal gut which could be a result of genetic defects or environmental assaults or both and NOT a problem widespread across the human species. That distinction is important and should not be forgotten or rolled into a BLANKET STATEMENT in the eager attempt to quickly find the culprit that one can then publicly hang on the gallows (cow’s milk in this case).

  3. Thank you for your presentation. I was diagnosed with Hashimotos Disease five years ago. My symptoms progressed, and I was given Levothyroxin in increasing dosages. Unfortunately, my endocrinologist did not discuss diet. I moved to Germany last July. Within four months of moving, my antibodies were below 90. My new doctor asked me if I had been diagnosed properly in the US, but a sonogram of my thyroid confirmed the diagnosis. I feel great and do not suffer from many of the symptoms I experienced in the US. I still have mild rosacea and days when I have less energy, but changing my diet has helped me tremendously. I believe that the lack of GMO foods in Germany is also significant in the changes in my body.

  4. I'm all good here but I'm a little worried about peoples' pets. Once they think and know how good it is having a plant based diet, they think it's good for their pets. "WRONG!" Animals are made up different and so they need meat and bones. I'm not saying they shouldn't eat veggies, as they also need some plant material and so they do need it but remember folks, if you have a pet, look at their teeth and you'd see they are made to hunt, stalk, capture, kill, tear and eat their food. This food is MEAT! I give my 2 dogs the food that suits them. Don't feed your pets too much if all kibble which is simply junk food similar how junk food is not good for us, junk food is NOT good for your pets. Give them what they need and NOT what's easier for you. If you can't spend time to prepare food for your pets, then maybe you shouldn't have gotten a pet in the first place. Pets can get inflammation and allergies and cancer from wrong foods just as wrong foods are bad for us and cause sickness and disease. The bone you give your dog is natures' tooth brush. Just thought I'd let you know as my research of the last 10 years for pets proven this. Fast foods for pets is like Fast food for us, IT'S NOT GOOD!

  5. The misinterpretation of the evidence at 6:50 is bizarre to me. If psoriasis is seen only seen in 2.8% of the general population, but seen in 17% of people whose siblings have it, there is a very clear correlation between having a sibling with psoriasis and getting it yourself. Although it's not a certainty you will get it, if you have a sibling with the disease you are about six times as likely to get it according to this data. The same principle applies to the rest of this chart.

  6. am i getting this right, she's an anti-vaxxer? she should be disqualified from promoting any type of advice, a lot of these doctors are problematic in some way, but at this point, anti-vaccine bs is just dangerous.

  7. Can the Hypothyroid be stopped or reversed with Plant Based Diet? Have been on Armour Thyroid and no help.

  8. I went whole food no processed foods, no corn, wheat, GMO SOY and I am a different person. 40 lbs thinner in 8 months, no more fatty liver disease, gurd, acid reflux, high blood pressure, high blood sugar, high cholesterol, arthritis, asthma, allergies ALL GONE! The down side? I keep talking about it all the time, I had to join a gym to burn off all my excess energy, I feel and act like I am 20, my face still looks 60! LOL, my face is 60! Please, please, please EAT YOUR VEGETABLES, even just eating more vegetables, a few bites at each meal and you will be doing your body a lot of good.

  9. Fat and oil doesn't make you fat!!! That's bullshit. Some of the fattest animals (e.g. hippos) eat only green plants and grasses. An avocado won't make you fat. Your minimally processed food and breads will! Bread 100% will. Look at ketosis patients or high fat diets, people's weight falls off. Bread = fat. Low fat is SO OVER

  10. Why would you put bread and minimally processed foods before nuts and olive oil?!? Bread is the most evil food on the face of the earth

  11. I REALLY like Dr. Popper’s personality. Great stage presence. Knows what she is talking about. So pleasant to listen to. So glad I discovered her. 😊😊

  12. Very blasé about vaccines… Need more info as to why her position is so at odds with mainstream science (not saying that because something is mainstream it is right…)

  13. I do not seek attention by having an auto-immune issue. I have been keeping food diaries/journals, trying different diets (spending lots of money). I WANT TO GET BETTER!!!

    I used to run daily, eat out socially, have loads of energy and that has change. Oh how bad I want that back.

  14. Dr. Popper, fucking genius, pardon my french. I've seen her in a couple of documentaries and it's so refreshing to see a woman who feels she needs to EDUCATE the mass popn rather than MEDICATE the mass popn. We need more of her kind, where are they??? crickets Right, not many eh? Hope she comes to Canada, I'd pay a henfty fine just to see her talk and educate us.

  15. Fat is needed for a healthy healing body. This video is not at all how I reversed my RA diagnosis . I am on a very high fat and very low carb diet. Lost all excess body fat AND RA symptoms. go figure.

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